Cryo-EM structure of ATP13A2 in the E1-ATP state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8iek
Q-score: 0.377
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the e1-atp state (Complex from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E1-like state
Resolution: 5.65 Å
EM Method: Single-particle
Fitted PDBs: 8iel
Q-score: 0.229
Cryo-EM structure of ATP13A2 in the E2P state
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8iem
Q-score: 0.262
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Spermine (202 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Beryllium trifluoride ion (66 Da, Ligand)
- Polyamine-transporting atpase 13a2 (123 kDa, Protein from Homo sapiens)
- Polyamine-transporting atpase 13a2 (Complex from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E2-Pi state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8ien
Q-score: -0.047
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Spermine (202 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Cryo-em structure of atp13a2 in the e2-pi state (Complex from Homo sapiens)
Cryo-EM structure of ATP13A2 in the nominal E1P state
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 8ieo
Q-score: 0.312
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the nominal e1p state (Complex from Homo sapiens)
- Spermine (202 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
Cryo-EM structure of ATP13A2 in the putative of E2 state
Resolution: 4.87 Å
EM Method: Single-particle
Fitted PDBs: 8ier
Q-score: 0.162
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Spermine (202 Da, Ligand)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the putative of e2 state (Complex from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E1P-ADP state
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8ies
Q-score: 0.308
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Cryo-em structure of atp13a2 in the e1p-adp state (Complex from Homo sapiens)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Polyamine-transporting atpase 13a2 (125 kDa, Protein from Homo sapiens)