Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with Gi1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7xbw
Q-score: 0.468
Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q
Sci Adv (2022) 8 pp. eabn8048-eabn8048 [ DOI: doi:10.1126/sciadv.abn8048 Pubmed: 35767622 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Chemokine receptor cx3cr1 in complex with gi1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Cx3c chemokine receptor 1 (41 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7xbx
Q-score: 0.361
Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q
Sci Adv (2022) 8 pp. eabn8048-eabn8048 [ DOI: doi:10.1126/sciadv.abn8048 Pubmed: 35767622 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Chemokine receptor cx3cr1 in complex with cx3cl1 gi1 (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Processed fractalkine,cx3c chemokine receptor 1 (51 kDa, Protein from Homo sapiens)
Cryo-EM structure of inactive mGlu2 homodimer
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7epa
Q-score: 0.311
Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, Zhou Y, Pin JP, Rondard P, Liu H, Liu J, Sun F, Wu B, Zhao Q
Nature (2021) 594 pp. 589-593 [ DOI: doi:10.1038/s41586-021-03641-w Pubmed: 34135509 ]
- Metabotropic glutamate receptor 2 (91 kDa, Protein from Homo sapiens)
- Inactive mglu2 homodimer (Complex from Homo sapiens)
Cryo-EM structure of LY354740-bound mGlu2 homodimer
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7epb
Q-score: 0.377
Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, Zhou Y, Pin JP, Rondard P, Liu H, Liu J, Sun F, Wu B, Zhao Q
Nature (2021) 594 pp. 589-593 [ DOI: doi:10.1038/s41586-021-03641-w Pubmed: 34135509 ]
- Ly354740-bound mglu2 homodimer (Complex from Homo sapiens)
- Metabotropic glutamate receptor 2 (94 kDa, Protein from Homo sapiens)
- (1s,2s,5r,6s)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (185 Da, Ligand)
- Anti-ron nanobody (15 kDa, Protein from Lama glama)
Cryo-EM structure of inactive mGlu7 homodimer
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7epc
Q-score: 0.214
Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, Zhou Y, Pin JP, Rondard P, Liu H, Liu J, Sun F, Wu B, Zhao Q
Nature (2021) 594 pp. 589-593 [ DOI: doi:10.1038/s41586-021-03641-w Pubmed: 34135509 ]
- Isoform 3 of metabotropic glutamate receptor 7 (96 kDa, Protein from Homo sapiens)
- Inactive mglu7 homodimer (Complex from Homo sapiens)
Cryo-EM structure of inactive mGlu2-7 heterodimer
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7epd
Q-score: 0.308