Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6agf
Q-score: 0.526
Pan X, Li Z, Zhou Q, Shen H, Wu K, Huang X, Chen J, Zhang J, Zhu X, Lei J, Xiong W, Gong H, Xiao B, Yan N
Science (2018) 362 [ Pubmed: 30190309 DOI: doi:10.1126/science.aau2486 ]
- Human sodium channel subunit beta-1 (Complex from Homo sapiens)
- Human sodium channel protein type 4 subunit alpha (Complex from Homo sapiens)
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of human sodium channel protein type 4 subunit alpha and human sodium channel subunit beta-1 (200 kDa, Complex)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- Sodium channel protein type 4 subunit alpha (212 kDa, Protein from Homo sapiens)
Cryo-EM map of the rabbit voltage-gated calcium channel Cav1.1 at 3.6 angstrom resolution
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5gjv
Q-score: 0.385
Wu JP, Yan Z, Li ZQ, Qian XY, Lu S, Dong MQ, Zhou Q, Yan N
Nature (2016) 537 pp. 191-196 [ DOI: doi:10.1038/nature19321 Pubmed: 27580036 ]
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (125 kDa, Protein from Oryctolagus cuniculus)
- Voltage-gated calcium channel cav1.1 (500 kDa, Complex from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel gamma-1 subunit (25 kDa, Protein from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-1 (22 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit alpha-1s (212 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit beta-1 (11 kDa, Protein from Oryctolagus cuniculus)
ClassII map of the rabbit voltage-gated calcium channel Cav1.1
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5gjw
Q-score: 0.36
Wu JP, Yan Z, Li ZQ, Qian XY, Lu S, Dong MQ, Zhou Q, Yan N
Nature (2016) 537 pp. 191-196 [ DOI: doi:10.1038/nature19321 Pubmed: 27580036 ]
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (125 kDa, Protein from Oryctolagus cuniculus)
- Voltage-gated calcium channel cav1.1 (500 kDa, Complex from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel gamma-1 subunit (25 kDa, Protein from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-1 (22 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit alpha-1s (212 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit beta-1 (11 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM map of RyR1 in a closed state (C1 conformer)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5gky
Q-score: 0.317
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM map of RyR1 in a closed state (C3 conformer)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5gkz
Q-score: 0.337
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM map of RyR1 in a closed state (C4 conformer)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 5gl0
Q-score: 0.309
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM map of RyR1 in an open state
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 5gl1
Q-score: 0.201
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)