Cryo-EM structure of Nav1.7 with RLZ
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8thg
Q-score: 0.483
Huang J, Fan X, Jin X, Teng L, Yan N
PNAS (2023) 120 pp. e2309773120-e2309773120 [ DOI: doi:10.1073/pnas.2309773120 Pubmed: 37782796 ]
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human voltage-gated sodium channel nav1.7 with beta subunits (Complex from Homo sapiens)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sodium channel protein type 9 subunit alpha (226 kDa, Protein from Homo sapiens)
- Sodium channel subunit beta-2 (24 kDa, Protein from Homo sapiens)
- 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine (234 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Cryo-EM structure of Nav1.7 with LTG
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8thh
Q-score: 0.511
Huang J, Fan X, Jin X, Teng L, Yan N
PNAS (2023) 120 pp. e2309773120-e2309773120 [ DOI: doi:10.1073/pnas.2309773120 Pubmed: 37782796 ]
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human voltage-gated sodium channel nav1.7 with beta subunits (Complex from Homo sapiens)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sodium channel protein type 9 subunit alpha (226 kDa, Protein from Homo sapiens)
- Sodium channel subunit beta-2 (24 kDa, Protein from Homo sapiens)
- (6m)-6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine (256 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Cryo-EM structure of human voltage-gated sodium channel Nav1.6
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8fhd
Q-score: 0.459
PNAS (2023) 120 pp. e2220578120-e2220578120 [ Pubmed: 36696443 DOI: doi:10.1073/pnas.2220578120 ]
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- Complex of human voltage-gated sodium channel nav1.6 with auxiliary beta-1 subunit (Complex from Homo sapiens)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- (5e,17r,20s)-23-amino-20-hydroxy-14,20-dioxo-15,19,21-trioxa-20lambda~5~-phosphatricos-5-en-17-yl hexadecanoate (661 Da, Ligand)
- Sodium channel protein type 8 subunit alpha (225 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
3.9 Angstrom reconstruction of E.coli AcrB embedded in the liposome
Proc. Natl. Acad. Sci. U.S.A. (2020) [ Pubmed: 32680969 DOI: 10.1073/pnas.2009385117 ]
Image sets:
3.9 Angstrom reconstruction of E.coli AcrB embedded in the liposome
PNAS (2020) 117 pp. 18497-18503 [ DOI: doi:10.1073/pnas.2009385117 Pubmed: 32680969 ]
- E.coli acrb (350 MDa, Complex from Escherichia coli)
