Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7mix
Q-score: 0.496
Nature (2021) 596 pp. 143-147 [ Pubmed: 34234349 DOI: doi:10.1038/s41586-021-03699-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Omega-conotoxin mviia (2 kDa, Protein from Conus magus)
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Cav2.2-ziconotide (Complex from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Voltage-dependent n-type calcium channel subunit alpha-1b (262 kDa, Protein from Homo sapiens)
- Cav2.2 (Complex from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (124 kDa, Protein from Homo sapiens)
Human N-type voltage-gated calcium channel Cav2.2 at 3.1 Angstrom resolution
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7miy
Q-score: 0.472
Nature (2021) 596 pp. 143-147 [ Pubmed: 34234349 DOI: doi:10.1038/s41586-021-03699-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Voltage-dependent n-type calcium channel subunit alpha-1b (262 kDa, Protein from Homo sapiens)
- Cav2.2 (Complex from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (124 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6p2p
Q-score: 0.462
Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, Du X, Yang H, Wong CCL, Yan N
Nature (2020) 581 pp. 333-338 [ Pubmed: 32433614 DOI: doi:10.1038/s41586-020-2290-0 ]
- S-{(3r,5r,9r)-1-[(2r,3s,4r,5r)-5-(6-amino-9h-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9z)-octadec-9-enethioate (non-preferred name) (1 kDa, Ligand)
- Acat1 (Complex from Homo sapiens)
- Sterol o-acyltransferase 1 (69 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6kzo
Q-score: 0.508
Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, Pan X, Yan N
Nature (2019) 576 pp. 492-497 [ Pubmed: 31766050 DOI: doi:10.1038/s41586-019-1801-3 ]
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Membrane protein (Complex from Homo sapiens)
- Voltage-dependent t-type calcium channel subunit alpha-1g (250 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
Cryo-EM map of the rabbit voltage-gated calcium channel Cav1.1 at 3.6 angstrom resolution
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5gjv
Q-score: 0.385
Wu JP, Yan Z, Li ZQ, Qian XY, Lu S, Dong MQ, Zhou Q, Yan N
Nature (2016) 537 pp. 191-196 [ DOI: doi:10.1038/nature19321 Pubmed: 27580036 ]
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (125 kDa, Protein from Oryctolagus cuniculus)
- Voltage-gated calcium channel cav1.1 (500 kDa, Complex from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel gamma-1 subunit (25 kDa, Protein from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-1 (22 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit alpha-1s (212 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit beta-1 (11 kDa, Protein from Oryctolagus cuniculus)
ClassII map of the rabbit voltage-gated calcium channel Cav1.1
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5gjw
Q-score: 0.36
Wu JP, Yan Z, Li ZQ, Qian XY, Lu S, Dong MQ, Zhou Q, Yan N
Nature (2016) 537 pp. 191-196 [ DOI: doi:10.1038/nature19321 Pubmed: 27580036 ]
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (125 kDa, Protein from Oryctolagus cuniculus)
- Voltage-gated calcium channel cav1.1 (500 kDa, Complex from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel gamma-1 subunit (25 kDa, Protein from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-1 (22 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit alpha-1s (212 kDa, Protein from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit beta-1 (11 kDa, Protein from Oryctolagus cuniculus)