Cryo-EM structure of L-fucokinase,GDP-fucose pyrophosphorylase (FKP) in Bacteroides fragilis
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 5yys
Q-score: 0.224
Liu Y, Hu H, Wang J, Zhou Q, Wu P, Yan N, Wang HW, Wu JW, Sun L
Protein Cell (2019) 10 pp. 365-369 [ Pubmed: 30242642 DOI: doi:10.1007/s13238-018-0576-x ]
- Fkp (Complex from Bacteroides fragilis)
- L-fucokinase, l-fucose-1-p guanylyltransferase (105 kDa, Protein from Bacteroides fragilis)
Cryo EM structure of human SEIPIN
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6ds5
Q-score: 0.473
Yan R, Qian H, Lukmantara I, Gao M, Du X, Yan N, Yang H
Dev Cell (2018) 47 pp. 248-256.e4 [ DOI: doi:10.1016/j.devcel.2018.09.010 Pubmed: 30293840 ]
- Seipin (45 kDa, Protein from Homo sapiens)
- Seipin (Cellular component from Homo sapiens)
Cryo-EM structure of a P-type ATPase
Resolution: 4.11 Å
EM Method: Single-particle
Fitted PDBs: 6a69
Q-score: 0.386
Gong D, Chi X, Ren K, Huang G, Zhou G, Yan N, Lei J, Zhou Q
Nat Commun (2018) 9 pp. 3623-3623 [ DOI: doi:10.1038/s41467-018-06075-7 Pubmed: 30190470 ]
- Neuroplastin (31 kDa, Protein from Homo sapiens)
- Complex of one pmca1 molecular with one nptn molecular (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Plasma membrane calcium-transporting atpase 1 (140 kDa, Protein from Homo sapiens)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6a90
Q-score: 0.56
Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith JJ, Chin YKY, Lei J, Zhou Q, King GF, Yan N
Science (2018) 362 [ DOI: doi:10.1126/science.aau2596 Pubmed: 30049784 ]
- Sodium channel protein pafpc1 (183 kDa, Protein from Periplaneta americana)
- Sodium ion (22 Da, Ligand)
- Voltage-gated sodium channel navpas from american cockroach periplaneta americana (Complex from Periplaneta americana)
- Dc1a (Complex from Diguetia canities)
- Complex of voltage-gated sodium channel navpas from american cockroach periplaneta americana and dc1a (200 kDa, Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Mu-diguetoxin-dc1a (6 kDa, Protein from Diguetia canities)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6a91
Q-score: 0.515
Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith JJ, Chin YKY, Lei J, Zhou Q, King GF, Yan N
Science (2018) 362 [ DOI: doi:10.1126/science.aau2596 Pubmed: 30049784 ]
- Sodium channel protein pafpc1 (183 kDa, Protein from Periplaneta americana)
- Water (18 Da, Ligand)
- Voltage-gated sodium channel navpas from american cockroach periplaneta americana (Complex from Periplaneta americana)
- [(3as,4r,10as)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3h,8h-pyrrolo[1,2-c]purin-4-yl]methyl carbamate (299 Da, Ligand)
- Dc1a (Complex from Diguetia canities)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of voltage-gated sodium channel navpas from american cockroach periplaneta americana bound with saxitoxin and dc1a (200 kDa, Complex)
- Mu-diguetoxin-dc1a (6 kDa, Protein from Diguetia canities)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 6a95
Q-score: 0.565
Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith JJ, Chin YKY, Lei J, Zhou Q, King GF, Yan N
Science (2018) 362 [ DOI: doi:10.1126/science.aau2596 Pubmed: 30049784 ]
- Sodium channel protein pafpc1 (183 kDa, Protein from Periplaneta americana)
- Sodium ion (22 Da, Ligand)
- Water (18 Da, Ligand)
- Voltage-gated sodium channel navpas from american cockroach periplaneta americana (Complex from Periplaneta americana)
- (1r,5r,6r,7r,9s,11s,12s,13s,14s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name) (319 Da, Ligand)
- Dc1a (Complex from Diguetia canities)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of voltage-gated sodium channel navpas from american cockroach periplaneta americana bound with saxitoxin and dc1a (200 kDa, Complex)
- Mu-diguetoxin-dc1a (6 kDa, Protein from Diguetia canities)
Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6agf
Q-score: 0.526
Pan X, Li Z, Zhou Q, Shen H, Wu K, Huang X, Chen J, Zhang J, Zhu X, Lei J, Xiong W, Gong H, Xiao B, Yan N
Science (2018) 362 [ Pubmed: 30190309 DOI: doi:10.1126/science.aau2486 ]
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- Complex of human sodium channel protein type 4 subunit alpha and human sodium channel subunit beta-1 (200 kDa, Complex)
- Sodium channel protein type 4 subunit alpha (212 kDa, Protein from Homo sapiens)
- Human sodium channel protein type 4 subunit alpha (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human sodium channel subunit beta-1 (Complex from Homo sapiens)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
Cryo-EM structure of human Ptch1
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6dmb
Q-score: 0.408
Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N
Science (2018) 361 [ Pubmed: 29954986 DOI: doi:10.1126/science.aas8935 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Patch1 (Cellular component from Homo sapiens)
- Protein patched homolog 1 (150 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
Cryo-EM structure of human Ptch1 with three mutations L282Q/T500F/P504L
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6dmo
Q-score: 0.279
Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N
Science (2018) 361 [ Pubmed: 29954986 DOI: doi:10.1126/science.aas8935 ]
- Patch1 with l282q/t500f/p504l mutations (Cellular component from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Protein patched homolog 1 (150 kDa, Protein from Homo sapiens)
Cryo-EM structure of human Ptch1 and ShhN complex
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6dmy
Q-score: 0.388
Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N
Science (2018) 361 [ Pubmed: 29954986 DOI: doi:10.1126/science.aas8935 ]
- Protein patched homolog 1 (150 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Patch1 (Cellular component from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Serine (105 Da, Ligand)
- Sonic hedgehog protein (19 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)