Cryo-EM structure of Scap/Insig complex in the present of digitonin.
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7etw
Q-score: 0.351
Yan R, Cao P, Song W, Li Y, Wang T, Qian H, Yan C, Yan N
Cell Rep (2021) 35 pp. 109299- [ DOI: doi:10.1016/j.celrep.2021.109299 ]
- Insulin-induced gene 2 protein (24 kDa, Protein from Homo sapiens)
- Sterol regulatory element-binding protein cleavage-activating protein (81 kDa, Protein from Homo sapiens)
- Digitonin (1 kDa, Ligand)
- Scap and insig complex (Complex from Homo sapiens)
Structure of RyR2 (F/A/C/Ca2+ dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6ji0
Q-score: 0.322
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 (Complex from Sus scrofa)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
Structure of RyR2 (F/A/C/L-Ca2+/apo-CaM-M dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6jii
Q-score: 0.319
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and apo-calmodulin-mimicking mutant (Complex from Sus scrofa)
Structure of RyR2 (F/A/C/L-Ca2+/Ca2+CaM dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6jiu
Q-score: 0.303
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and ca2+-loaded calmodulin at low ca2+ concentrations (Complex from Sus scrofa)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Structure of RyR2 (P/L-Ca2+/Ca2+-CaM dataset)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6jv2
Q-score: 0.267
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Ryr2 in complex with calmodulin (Complex from Sus scrofa)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Cryo-EM structure of L-fucokinase,GDP-fucose pyrophosphorylase (FKP) in Bacteroides fragilis
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 5yys
Q-score: 0.224
Liu Y, Hu H, Wang J, Zhou Q, Wu P, Yan N, Wang HW, Wu JW, Sun L
Protein Cell (2019) 10 pp. 365-369 [ Pubmed: 30242642 DOI: doi:10.1007/s13238-018-0576-x ]
- L-fucokinase, l-fucose-1-p guanylyltransferase (105 kDa, Protein from Bacteroides fragilis)
- Fkp (Complex from Bacteroides fragilis)
Cryo-EM structure of RyR2 in closed state
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 5go9
Q-score: 0.252
Cryo-EM structure of RyR2 in open state
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 5goa
Q-score: 0.245
cryo-EM map of the full-length human NPC1 at 4.4 angstrom
Resolution: 4.43 Å
EM Method: Single-particle
Fitted PDBs: 3jd8
Q-score: 0.224