Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8amw
Q-score: 0.594
Huang P, Venskutonyte R, Prasad RB, Ardalani H, de Mare SW, Fan X, Li P, Spegel P, Yan N, Gourdon P, Artner I, Lindkvist-Petersson K
Nat Commun (2023) 14 pp. 600-600 [ Pubmed: 36737436 DOI: doi:10.1038/s41467-023-36272-y ]
- Dimer of tetramers (Complex from Homo sapiens)
- Aquaporin-7 (37 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Glycerol (92 Da, Ligand)
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8amx
Q-score: 0.663
Huang P, Venskutonyte R, Prasad RB, Ardalani H, de Mare SW, Fan X, Li P, Spegel P, Yan N, Gourdon P, Artner I, Lindkvist-Petersson K
Nat Commun (2023) 14 pp. 600-600 [ Pubmed: 36737436 DOI: doi:10.1038/s41467-023-36272-y ]
- Dimer of tetramers (Complex from Homo sapiens)
- Aquaporin-7 (37 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Human R-type voltage-gated calcium channel Cav2.3 at 3.1 Angstrom resolution
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8epl
Q-score: 0.472
Yao X, Wang Y, Wang Z, Fan X, Wu D, Huang J, Mueller A, Gao S, Hu M, Robinson CV, Yu Y, Gao S, Yan N
Nat Commun (2022) 13 pp. 7358-7358 [ DOI: doi:10.1038/s41467-022-35026-6 Pubmed: 36446785 ]
- Voltage-dependent r-type calcium channel subunit alpha-1e (262 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Voltage-dependent l-type calcium channel subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Cav2.3 (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (124 kDa, Protein from Homo sapiens)
Human R-type voltage-gated calcium channel Cav2.3 CH2II-deleted mutant at 3.1 Angstrom resolution
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8epm
Q-score: 0.512
Yao X, Wang Y, Wang Z, Fan X, Wu D, Huang J, Mueller A, Gao S, Hu M, Robinson CV, Yu Y, Gao S, Yan N
Nat Commun (2022) 13 pp. 7358-7358 [ DOI: doi:10.1038/s41467-022-35026-6 Pubmed: 36446785 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent r-type calcium channel subunit alpha-1e (262 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Cav2.3 (Complex from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (124 kDa, Protein from Homo sapiens)
Cryo-EM structure of human glucose transporter GLUT4 bound to cytochalasin B in lipid nanodiscs
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7wsm
Q-score: 0.502
Yuan Y, Kong F, Xu H, Zhu A, Yan N, Yan C
Nat Commun (2022) 13 pp. 2671-2671 [ DOI: doi:10.1038/s41467-022-30235-5 Pubmed: 35562357 ]
- Solute carrier family 2, facilitated glucose transporter member 4 (56 kDa, Protein from Homo sapiens)
- Glut4 (56 MDa, Complex from Homo sapiens)
- Cytochalasin b (479 Da, Ligand)
Cryo-EM structure of human glucose transporter GLUT4 bound to cytochalasin B in detergent micelles
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 7wsn
Q-score: 0.496
Yuan Y, Kong F, Xu H, Zhu A, Yan N, Yan C
Nat Commun (2022) 13 pp. 2671-2671 [ DOI: doi:10.1038/s41467-022-30235-5 Pubmed: 35562357 ]
- Solute carrier family 2, facilitated glucose transporter member 4 (56 kDa, Protein from Homo sapiens)
- Glut4 (56 MDa, Complex from Homo sapiens)
- Cytochalasin b (479 Da, Ligand)
Cryo-EM structure of SLC40/ferroportin in complex with Fab
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6vyh
Q-score: 0.532
Pan Y, Ren Z, Gao S, Shen J, Wang L, Xu Z, Yu Y, Bachina P, Zhang H, Fan X, Laganowsky A, Yan N, Zhou M
Nat Commun (2020) 11 pp. 5686-5686 [ DOI: doi:10.1038/s41467-020-19458-6 Pubmed: 33173040 ]
- 11f9 light-chain (23 kDa, Protein from Mus musculus)
- Solute carrier family 40 protein (63 kDa, Protein from Carlito syrichta)
- Cryo-em map of slc40/ferroportin in complex with fab (Complex from Carlito syrichta)
- Cobalt (ii) ion (58 Da, Ligand)
- 11f9 heavy-chain (25 kDa, Protein from Mus musculus)
- Water (18 Da, Ligand)
Cryo-EM structure of SLC40/ferroportin with Fab in the presence of hepcidin
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6wik
Q-score: 0.384
Pan Y, Ren Z, Gao S, Shen J, Wang L, Xu Z, Yu Y, Bachina P, Zhang H, Fan X, Laganowsky A, Yan N, Zhou M
Nat Commun (2020) 11 pp. 5686-5686 [ DOI: doi:10.1038/s41467-020-19458-6 Pubmed: 33173040 ]
- Cryo-em map of slc40/ferroportin with fab in the presence of hepcidin (Complex from Carlito syrichta)
- 11f9 fab heavy-chain (25 kDa, Protein from Mus musculus)
- 11f9 fab light-chain (23 kDa, Protein from Mus musculus)
- Solute carrier family 40 protein (63 kDa, Protein from Carlito syrichta)
Cryo-EM structure of tetrameric Ptch1 in complex with ShhNp (form I)
Resolution: 6.8 Å
EM Method: Single-particle
Fitted PDBs: 6n7g
Q-score: 0.132
Qian H, Cao P, Hu M, Gao S, Yan N, Gong X
Nat Commun (2019) 10 pp. 2320-2320 [ DOI: doi:10.1038/s41467-019-10234-9 Pubmed: 31127104 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Patch1 (Cellular component from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Protein patched homolog 1 (150 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Sonic hedgehog protein (19 kDa, Protein from Homo sapiens)
Cryo-EM structure of the 2:1 hPtch1-Shhp complex
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6n7h
Q-score: 0.408
Qian H, Cao P, Hu M, Gao S, Yan N, Gong X
Nat Commun (2019) 10 pp. 2320-2320 [ DOI: doi:10.1038/s41467-019-10234-9 Pubmed: 31127104 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Patch1 (Cellular component from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Protein patched homolog 1 (150 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Sonic hedgehog protein (19 kDa, Protein from Homo sapiens)