Cryo-EM structure of human HCN3 channel with cAMP
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8io0
Q-score: 0.42
Cryo-EM structure of human HCN3 channel in apo state
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8inz
Q-score: 0.526
Yu B, Lu Q, Li J, Cheng X, Hu H, Li Y, Che T, Hua Y, Jiang H, Zhang Y, Xian C, Yang T, Fu Y, Chen Y, Nan W, McCormick PJ, Xiong B, Duan J, Zeng B, Li Y, Fu Y, Zhang J
J Biol Chem (2024) 300 pp. 107288-107288 [ Pubmed: 38636662 DOI: doi:10.1016/j.jbc.2024.107288 ]
- 4-[[(2~{s},4~{a}~{r},6~{s},8~{a}~{s})-6-[(4~{s},5~{r})-4-[(2~{s})-butan-2-yl]-5,9-dimethyl-decyl]-4~{a}-methyl-2,3,4,5,6,7,8,8~{a}-octahydro-1~{h}-naphthalen-2-yl]oxy]-4-oxidanylidene-butanoic acid (492 Da, Ligand)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (86 kDa, Protein from Homo sapiens)
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Complex from Homo sapiens)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8heb
Q-score: 0.379
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hec
Q-score: 0.358
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8hed
Q-score: 0.469
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein rbd complex with 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 spike glycoprotein rbd (Complex from Oryctolagus cuniculus)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6k32
Q-score: 0.395
Li X, Wang L, Wang X, Chen W, Yang T, Song J, Liu H, Cheng L
J Mol Biol (2020) 432 pp. 358-366 [ DOI: doi:10.1016/j.jmb.2019.09.015 Pubmed: 31629769 ]
- Rna-dependent rna polymerase (137 kDa, Protein from Cypovirus 1)
- Vp1 (136 kDa, Protein from Cypovirus 1)
- Magnesium ion (24 Da, Ligand)
- Vp1 (137 kDa, Protein from Cypovirus 1)
- Diphosphate (173 Da, Ligand)
- 2'-o-methyladenosine 5'-(dihydrogen phosphate) (361 Da, Ligand)
- Cypovirus (Virus from Cypovirus)
- Rna (5'-d(*(3po))-r(*ap*g)-3' (869 Da, RNA from Cypovirus 1)
- Uridine 5'-triphosphate (484 Da, Ligand)
- Rna (5'-r(p*up*up*ap*cp*u)-3') (1 kDa, RNA from Cypovirus 1)
- Vp1 (135 kDa, Protein from Cypovirus 1)
- Viral structural protein 4 (63 kDa, Protein from Cypovirus 1)
- 7-methylguanosine (298 Da, Ligand)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5zvs
Q-score: 0.511
Wang X, Zhang F, Su R, Li X, Chen W, Chen Q, Yang T, Wang J, Liu H, Fang Q, Cheng L
PNAS (2018) 115 pp. 7344-7349 [ Pubmed: 29941585 DOI: doi:10.1073/pnas.1803885115 ]
- Putative core protein ntpase/vp5 (80 kDa, Protein from Grass carp reovirus)
- Vp2 (141 kDa, Protein from Grass carp reovirus)
- Vp3 (132 kDa, Protein from Grass carp reovirus)
- Grass carp reovirus (Virus from Grass carp reovirus)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 5zvt
Q-score: 0.195
Wang X, Zhang F, Su R, Li X, Chen W, Chen Q, Yang T, Wang J, Liu H, Fang Q, Cheng L
PNAS (2018) 115 pp. 7344-7349 [ Pubmed: 29941585 DOI: doi:10.1073/pnas.1803885115 ]
- N-terminus of outer capsid protein vp5 (4 kDa, Protein from Grass carp reovirus)
- Vp1 (141 kDa, Protein from Grass carp reovirus)
- C-terminus of outer capsid protein vp5 (64 kDa, Protein from Grass carp reovirus)
- Vp3 (132 kDa, Protein from Grass carp reovirus)
- Outer capsid vp7 (29 kDa, Protein from Grass carp reovirus)
- Core protein vp6 (44 kDa, Protein from Grass carp reovirus)
- Myristic acid (228 Da, Ligand)
- Grass carp reovirus (Virus from Grass carp reovirus)