Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6dzv
Q-score: 0.207
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Ibogaine-bound wild type human serotonin transporter in complex with 15b8 fab (Complex)
- (5beta)-12-methoxyibogamine (310 Da, Ligand)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6dzw
Q-score: 0.174
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- Human serotonin transporter in complex with fab/fv bound to paroxetine (Complex)
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Paroxetine (329 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- 8b6 antibody single chain (26 kDa, Protein from Mus musculus)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
- 8b6 scfv (Complex from Mus musculus)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6dzy
Q-score: 0.256
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- Human serotonin transporter in complex with fab/fv bound to ibogaine (Complex)
- (5beta)-12-methoxyibogamine (310 Da, Ligand)
- 8b6 antibody single chain (26 kDa, Protein from Mus musculus)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
- 8b6 scfv (Complex from Mus musculus)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6dzz
Q-score: 0.336
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- Human serotonin transporter in complex with fab bound to ibogaine (Complex)
- Sodium-dependent serotonin transporter (61 kDa, Protein from Homo sapiens)
- (5beta)-12-methoxyibogamine (310 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)