Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6dzv
Q-score: 0.207
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Ibogaine-bound wild type human serotonin transporter in complex with 15b8 fab (Complex)
- (5beta)-12-methoxyibogamine (310 Da, Ligand)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6dzw
Q-score: 0.174
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- Human serotonin transporter in complex with fab/fv bound to paroxetine (Complex)
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Paroxetine (329 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- 8b6 antibody single chain (26 kDa, Protein from Mus musculus)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
- 8b6 scfv (Complex from Mus musculus)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6dzy
Q-score: 0.256
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- Human serotonin transporter in complex with fab/fv bound to ibogaine (Complex)
- (5beta)-12-methoxyibogamine (310 Da, Ligand)
- 8b6 antibody single chain (26 kDa, Protein from Mus musculus)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
- 8b6 scfv (Complex from Mus musculus)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6dzz
Q-score: 0.336
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- Human serotonin transporter in complex with fab bound to ibogaine (Complex)
- Sodium-dependent serotonin transporter (61 kDa, Protein from Homo sapiens)
- (5beta)-12-methoxyibogamine (310 Da, Ligand)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
Resolution: 5.97 Å
EM Method: Single-particle
Fitted PDBs: 6mm9
Q-score: 0.211
Jalali-Yazdi F, Chowdhury S, Yoshioka C, Gouaux E
Cell (2018) 175 pp. 1520-1532.e15 [ DOI: doi:10.1016/j.cell.2018.10.043 Pubmed: 30500536 ]
- Glutamate receptor ionotropic, nmda 2a (93 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Diheteromeric nmda receptor glun1/glun2a in the '1-knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at ph 6.1 (500 kDa, Complex from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Rattus norvegicus)
Resolution: 6.31 Å
EM Method: Single-particle
Fitted PDBs: 6mma
Q-score: 0.184
Jalali-Yazdi F, Chowdhury S, Yoshioka C, Gouaux E
Cell (2018) 175 pp. 1520-1532.e15 [ DOI: doi:10.1016/j.cell.2018.10.043 Pubmed: 30500536 ]
- Diheteromeric nmda receptor glun1/glun2a in the 'extended' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at ph 6.1 (500 kDa, Complex from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2a (93 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Rattus norvegicus)
Resolution: 12.7 Å
EM Method: Single-particle
Fitted PDBs: 6mmb
Q-score: 0.068
Jalali-Yazdi F, Chowdhury S, Yoshioka C, Gouaux E
Cell (2018) 175 pp. 1520-1532.e15 [ DOI: doi:10.1016/j.cell.2018.10.043 Pubmed: 30500536 ]
- Glutamate receptor ionotropic, nmda 2a (93 kDa, Protein from Rattus norvegicus)
- Diheteromeric nmda receptor glun1/glun2a in the 'super-splayed' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at ph 6.1 (500 kDa, Complex from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Rattus norvegicus)
Resolution: 6.23 Å
EM Method: Single-particle
Fitted PDBs: 6mmg
Q-score: 0.124
Jalali-Yazdi F, Chowdhury S, Yoshioka C, Gouaux E
Cell (2018) 175 pp. 1520-1532.e15 [ DOI: doi:10.1016/j.cell.2018.10.043 Pubmed: 30500536 ]
- Diheteromeric nmda receptor glun1/glun2a in the '2-knuckle-symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 milliomolar edta, and at ph 7.4 (500 kDa, Complex from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2a (93 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Rattus norvegicus)
Resolution: 8.21 Å
EM Method: Single-particle
Fitted PDBs: 6mmh
Q-score: 0.145
Jalali-Yazdi F, Chowdhury S, Yoshioka C, Gouaux E
Cell (2018) 175 pp. 1520-1532.e15 [ DOI: doi:10.1016/j.cell.2018.10.043 Pubmed: 30500536 ]
- Glutamate receptor ionotropic, nmda 2a (93 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Diheteromeric nmda receptor glun1/glun2a in the 'extended-2' conformation, in complex with glycine and glutamate, in the presence of 1 milliomolar zinc chloride, and at ph 7.4 (500 kDa, Complex from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Rattus norvegicus)