a peptide receptor complex structure
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 8xgo
Q-score: 0.535
Wu Z, Chen G, Qiu C, Yan X, Xu L, Jiang S, Xu J, Han R, Shi T, Liu Y, Gao W, Wang Q, Li J, Ye F, Pan X, Zhang Z, Ning P, Zhang B, Chen J, Du Y
Sci Adv (2024) 10 pp. eadn7771-eadn7771 [ Pubmed: 39151001 DOI: doi:10.1126/sciadv.adn7771 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Kiss1r (Complex)
- Scfv16 (Complex)
- Kissar-gq-scfv16 (130 kDa, Complex from Homo sapiens)
- Kiss1r,guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2,guanine nucleotide-binding protein g(q) subunit alpha (Complex)
- Kiss-1 receptor (42 kDa, Protein from Homo sapiens)
- Tak448 (1 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
a peptide receptor complex structure
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8xgs
Q-score: 0.475
Wu Z, Chen G, Qiu C, Yan X, Xu L, Jiang S, Xu J, Han R, Shi T, Liu Y, Gao W, Wang Q, Li J, Ye F, Pan X, Zhang Z, Ning P, Zhang B, Chen J, Du Y
Sci Adv (2024) 10 pp. eadn7771-eadn7771 [ Pubmed: 39151001 DOI: doi:10.1126/sciadv.adn7771 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2,guanine nucleotide-binding protein g(q) subunit alpha (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Kiss1r (Complex from Homo sapiens)
- Metastin (5 kDa, Protein from synthetic construct)
- Kiss-1 receptor (42 kDa, Protein from Homo sapiens)
- Kp54-kiss1r-gq-scfv16 (130 kDa, Complex from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
a peptide receptor complex structure
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8xgu
Q-score: 0.482
Wu Z, Chen G, Qiu C, Yan X, Xu L, Jiang S, Xu J, Han R, Shi T, Liu Y, Gao W, Wang Q, Li J, Ye F, Pan X, Zhang Z, Ning P, Zhang B, Chen J, Du Y
Sci Adv (2024) 10 pp. eadn7771-eadn7771 [ Pubmed: 39151001 DOI: doi:10.1126/sciadv.adn7771 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Homo sapiens)
- Kiss1r (Complex from Homo sapiens)
- Kiss-1 receptor (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Tak448 (1 kDa, Protein from synthetic construct)
- Kp54-kiss1r-gq-scfv16 (130 kDa, Complex from Homo sapiens)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2,guanine nucleotide-binding protein g(i) subunit alpha-1 (Complex from Homo sapiens)
Cryo-EM structure of Mycobacterium tuberculosis DppABCD in apo form
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8wd9
Q-score: 0.528
To Be Published
- Probable periplasmic dipeptide-binding lipoprotein dppa (56 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport integral membrane protein abc transporter dppb (32 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Palmitic acid (256 Da, Ligand)
- (2s)-1-(hexadecanoyloxy)propan-2-yl (10s)-10-methyloctadecanoate (594 Da, Ligand)
- Probable dipeptide-transport integral membrane protein abc transporter dppc (30 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Dppabcd (Complex from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport atp-binding protein abc transporter dppd (59 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
Cryo-EM structure of the substrate-bound DppABCD complex
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8wda
Q-score: 0.545
To Be Published
- Probable periplasmic dipeptide-binding lipoprotein dppa (56 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport integral membrane protein abc transporter dppb (32 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Palmitic acid (256 Da, Ligand)
- (2s)-1-(hexadecanoyloxy)propan-2-yl (10s)-10-methyloctadecanoate (594 Da, Ligand)
- Probable dipeptide-transport integral membrane protein abc transporter dppc (30 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Dppabcd (Complex from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport atp-binding protein abc transporter dppd (59 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Tetrapeptide (330 Da, Protein from Mycolicibacterium smegmatis MC2 155)
Cryo-EM structure of the ATP-bound DppABCD complex
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8wdb
Q-score: 0.605
To Be Published
- Probable periplasmic dipeptide-binding lipoprotein dppa (56 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport integral membrane protein abc transporter dppb (32 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport atp-binding protein abc transporter dppd (59 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport integral membrane protein abc transporter dppc (30 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Dppabcd (Complex from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of the ATP-bound Mtb DppABCD with the D445A mutation of DppA
Resolution: 3.89 Å
EM Method: Single-particle
Fitted PDBs: 8xfc
Q-score: 0.425
To Be Published
- Probable dipeptide-transport integral membrane protein abc transporter dppb (32 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable dipeptide-transport atp-binding protein abc transporter dppd (59 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Dppabcd (Complex from Mycobacterium tuberculosis H37Rv)
- Probable dipeptide-transport integral membrane protein abc transporter dppc (30 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Probable periplasmic dipeptide-binding lipoprotein dppa (56 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Adenosine-5'-triphosphate (507 Da, Ligand)
Cryo-EM structure of Mycobacterium tuberculosis OppABCD in the pre-translocation state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8j5q
Q-score: 0.519
Yang X, Hu T, Liang J, Xiong Z, Lin Z, Zhao Y, Zhou X, Gao Y, Sun S, Yang X, Guddat LW, Yang H, Rao Z, Zhang B
Nat Struct Mol Biol (2024) 31 pp. 1072-1082 [ DOI: doi:10.1038/s41594-024-01256-z Pubmed: 38548954 ]
- Putative peptide transport permease protein rv1283c (35 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre-translocation state (Complex from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Uncharacterized protein rv1280c (64 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Putative peptide transport permease protein rv1282c (31 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Endogenous oligopeptide (783 Da, Protein from Mycolicibacterium smegmatis MC2 155)
- Uncharacterized abc transporter atp-binding protein rv1281c (65 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Iron/sulfur cluster (351 Da, Ligand)
Cryo-EM structure of Mycobacterium tuberculosis OppABCD in the resting state
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 8j5r
Q-score: 0.534
Yang X, Hu T, Liang J, Xiong Z, Lin Z, Zhao Y, Zhou X, Gao Y, Sun S, Yang X, Guddat LW, Yang H, Rao Z, Zhang B
Nat Struct Mol Biol (2024) 31 pp. 1072-1082 [ DOI: doi:10.1038/s41594-024-01256-z Pubmed: 38548954 ]
- Putative peptide transport permease protein rv1283c (35 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Uncharacterized protein rv1280c (64 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Putative peptide transport permease protein rv1282c (31 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Iron/sulfur cluster (351 Da, Ligand)
- Uncharacterized abc transporter atp-binding protein rv1281c (65 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Cryo-em structure of mycobacterium tuberculosis oppabcd in the resting state (Complex from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
Cryo-EM structure of Mycobacterium tuberculosis OppABCD in the pre-catalytic intermediate state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8j5s
Q-score: 0.566
Yang X, Hu T, Liang J, Xiong Z, Lin Z, Zhao Y, Zhou X, Gao Y, Sun S, Yang X, Guddat LW, Yang H, Rao Z, Zhang B
Nat Struct Mol Biol (2024) 31 pp. 1072-1082 [ DOI: doi:10.1038/s41594-024-01256-z Pubmed: 38548954 ]
- Putative peptide transport permease protein rv1283c (35 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Endogenous oligopeptide (698 Da, Protein from Mycolicibacterium smegmatis MC2 155)
- Uncharacterized protein rv1280c (64 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Putative peptide transport permease protein rv1282c (31 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Uncharacterized abc transporter atp-binding protein rv1281c (65 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre-catalytic intermediate state (Complex from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Magnesium ion (24 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)