Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 7wiu
Q-score: 0.476
Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 7wiv
Q-score: 0.577
Sun S, Gao Y, Yang X, Yang X, Hu T, Liang J, Xiong Z, Ran Y, Ren P, Bai F, Guddat LW, Yang H, Rao Z, Zhang B
Protein Cell (2023) 14 pp. 448-458 [ Pubmed: 36882106 DOI: doi:10.1093/procel/pwac060 ]
- Mycobactin import atp-binding/permease protein irta (93 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Mycobactin import atp-binding/permease protein irtb (61 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Irtab (Complex from Mycobacterium tuberculosis H37Rv)
Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 7wiw
Q-score: 0.56
Sun S, Gao Y, Yang X, Yang X, Hu T, Liang J, Xiong Z, Ran Y, Ren P, Bai F, Guddat LW, Yang H, Rao Z, Zhang B
Protein Cell (2023) 14 pp. 448-458 [ Pubmed: 36882106 DOI: doi:10.1093/procel/pwac060 ]
- Mycobactin import atp-binding/permease protein irtb (61 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mycobactin import atp-binding/permease protein irta (93 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Irtab (Complex from Mycobacterium tuberculosis H37Rv)
Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with ADP
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 7wix
Q-score: 0.48
Sun S, Gao Y, Yang X, Yang X, Hu T, Liang J, Xiong Z, Ran Y, Ren P, Bai F, Guddat LW, Yang H, Rao Z, Zhang B
Protein Cell (2023) 14 pp. 448-458 [ Pubmed: 36882106 DOI: doi:10.1093/procel/pwac060 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Mycobactin import atp-binding/permease protein irta (93 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Mycobactin import atp-binding/permease protein irtb (61 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Magnesium ion (24 Da, Ligand)
- Irtab (Complex from Mycobacterium tuberculosis H37Rv)
Mycobacterium smegmatis SugABC complex
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7cad
Q-score: 0.505
Liu F, Liang J, Zhang B, Gao Y, Yang X, Hu T, Yang H, Xu W, Guddat LW, Rao Z
Sci Adv (2020) 6 [ DOI: doi:10.1126/sciadv.abb9833 Pubmed: 33127676 ]
- Mycobacterium smegmatis sugabc complex (Complex from Mycolicibacterium smegmatis MC2 155)
- Abc sugar transporter, permease component (32 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Abc transporter, atp-binding protein sugc (43 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Abc transporter, permease protein sugb (29 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
Mycobacterium smegmatis LpqY-SugABC complex in the resting state
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 7cae
Q-score: 0.491
Liu F, Liang J, Zhang B, Gao Y, Yang X, Hu T, Yang H, Xu W, Guddat LW, Rao Z
Sci Adv (2020) 6 [ DOI: doi:10.1126/sciadv.abb9833 Pubmed: 33127676 ]
- Abc sugar transporter, permease component (32 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Abc transporter, atp-binding protein sugc (43 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Bacterial extracellular solute-binding protein (50 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Mycobacterium smegmatis lpqy-sugabc complex in the resting state. (Complex from Mycolicibacterium smegmatis MC2 155)
- Abc transporter, permease protein sugb (29 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7caf
Q-score: 0.498
Liu F, Liang J, Zhang B, Gao Y, Yang X, Hu T, Yang H, Xu W, Guddat LW, Rao Z
Sci Adv (2020) 6 [ DOI: doi:10.1126/sciadv.abb9833 Pubmed: 33127676 ]
- Abc transporter, permease protein sugb (29 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Abc transporter, atp-binding protein sugc (43 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Bacterial extracellular solute-binding protein (50 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Abc sugar transporter, permease component (32 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Mycobacterium smegmatis lpqy-sugabc complex in the pre-translocation state (Complex from Mycolicibacterium smegmatis MC2 155)
Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 7cag
Q-score: 0.453
Liu F, Liang J, Zhang B, Gao Y, Yang X, Hu T, Yang H, Xu W, Guddat LW, Rao Z
Sci Adv (2020) 6 [ DOI: doi:10.1126/sciadv.abb9833 Pubmed: 33127676 ]
- Mycobacterium smegmatis lpqy-sugabc complex in the catalytic intermediate state (Complex from Mycolicibacterium smegmatis MC2 155)
- Abc sugar transporter, permease component (32 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Abc transporter, atp-binding protein sugc (43 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Bacterial extracellular solute-binding protein (50 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Abc transporter, permease protein sugb (29 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))