CryoEM structure of human XPR1 in complex with phosphate in state A
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j51
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state B
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j52
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state C
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j53
Q-score: 0.413
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Human xpr1 (Complex from Homo sapiens)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9jm0
Q-score: 0.492
Wang Y, Wang C, Guan Z, Cao J, Xu J, Wang S, Cui Y, Wang Q, Chen Y, Yin Y, Zhang D, Liu H, Sun M, Jin S, Tao P, Zou T
Cell Rep (2024) 43 pp. 114857-114857 [ Pubmed: 39395169 DOI: doi:10.1016/j.celrep.2024.114857 ]
- Rna (5'-r(p*cp*gp*up*ap*ap*gp*gp*gp*up*gp*cp*gp*cp*a)-3') (4 kDa, RNA from Escherichia coli)
- Rna (82-mer) (26 kDa, RNA from Escherichia coli)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Nicotinamide (122 Da, Ligand)
- Dna (85-mer) (26 kDa, DNA from Escherichia coli)
- Retron ec86-effector fiber (Complex from Escherichia coli)
- Retron ec86 reverse transcriptase (37 kDa, Protein from Escherichia coli)
- Retron ec86 putative ribosyltransferase/dna-binding protein (35 kDa, Protein from Escherichia coli)
CryoEM structure of human XPR1 in apo state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9j4x
Q-score: 0.554
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ Pubmed: 39747008 DOI: doi:10.1038/s41467-024-55471-9 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
Portal protein of empty Haloferax tailed virus 1.
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8qsi
Q-score: 0.532
Zhang D, Daum B, Isupov MN, McLaren M, Oksanen H, Quax TEF, Schwarzer S, Gold VAM, Antson A
To Be Published
- Portal protein (75 kDa, Protein from Haloferax tailed virus 1)
- Hk97 gp6-like/spp1 gp15-like head-tail connector (15 kDa, Protein from Haloferax tailed virus 1)
- Haloferax tailed virus 1 (Virus from Haloferax tailed virus 1)
- Magnesium ion (24 Da, Ligand)
Portal capsid interface of full Haloferax tailed virus 1.
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 8qsy
Q-score: 0.571
Zhang D, Daum B, Isupov MN, McLaren M, Oksanen H, Quax TEF, Schwarzer S, Gold VAM, Antson A
To Be Published
- Hk97 gp6-like/spp1 gp15-like head-tail connector (15 kDa, Protein from Haloferax tailed virus 1)
- Magnesium ion (24 Da, Ligand)
- Haloferax tailed virus 1 (Virus from Haloferax tailed virus 1)
- Portal protein (75 kDa, Protein from Haloferax tailed virus 1)
- Hk97 gp5-like major capsid protein (43 kDa, Protein from Haloferax tailed virus 1)
- Capsid stabilization protein (13 kDa, Protein from Haloferax tailed virus 1)
- Hypothetical protein gp21 (9 kDa, Protein from Haloferax tailed virus 1)
- Potassium ion (39 Da, Ligand)
Portal protein of full Haloferax tailed virus 1.
Resolution: 2.342 Å
EM Method: Single-particle
Fitted PDBs: 8qqn
Q-score: 0.561
Zhang D, Daum B, Isupov MN, McLaren M, Oksanen H, Quax TEF, Schwarzer S, Gold VAM, Antson A
To Be Published
- Portal protein (75 kDa, Protein from Haloferax tailed virus 1)
- Hk97 gp6-like/spp1 gp15-like head-tail connector (15 kDa, Protein from Haloferax tailed virus 1)
- Haloferax tailed virus 1 (Virus from Haloferax tailed virus 1)
- Magnesium ion (24 Da, Ligand)
Turret of Haloferax tailed virus 1
Resolution: 2.36 Å
EM Method: Single-particle
Fitted PDBs: 8qpg
Q-score: 0.588
Zhang D, Daum B, Isupov MN, McLaren M, Oksanen H, Quax TEF, Schwarzer S, Gold VAM, Antson A
To Be Published
- Prokaryotic polysaccharide deacetylase (45 kDa, Protein from Haloferax tailed virus 1)
- Zinc ion (65 Da, Ligand)
- Haloferax tailed virus 1 (Virus from Haloferax tailed virus 1)
- Magnesium ion (24 Da, Ligand)
- Gp30 (12 kDa, Protein from Haloferax tailed virus 1)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8qpq
Q-score: 0.538
Zhang D, Daum B, Isupov MN, McLaren M, Oksanen H, Quax TEF, Schwarzer S, Gold VAM, Antson A
To Be Published
- Prokaryotic polysaccharide deacetylase (45 kDa, Protein from Haloferax tailed virus 1)
- Zinc ion (65 Da, Ligand)
- Haloferax tailed virus 1 (Virus from Haloferax tailed virus 1)
- Magnesium ion (24 Da, Ligand)
- Hk97 gp5-like major capsid protein (43 kDa, Protein from Haloferax tailed virus 1)
- Gp30 (12 kDa, Protein from Haloferax tailed virus 1)