Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Enterovirus 71 a-particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Enterovirus a71 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- The fab of h1a6.2 (Complex from Mus)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Capsid protein vp4 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (7 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 mature virion in complex with fab h1a6.2 (Complex)
- The fab of h1a6.2 (Complex from Mus)
Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Coxsackievirus a16 a-particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8w20
Q-score: 0.295
Zhao Q, Bertolli S, Park YJ, Tan Y, Cutler KJ, Srinivas P, Asfahl KL, Fonesca-Garcia C, Gallagher LA, Li Y, Wang Y, Coleman-Derr D, DiMaio F, Zhang D, Peterson SB, Veesler D, Mougous JD
Nature (2024) 629 pp. 165-173 [ Pubmed: 38632398 DOI: doi:10.1038/s41586-024-07298-z ]
- Umb1 umbrella toxin particle (Complex from Streptomyces coelicolor A3(2))
- Secreted protein (17 kDa, Protein from Streptomyces coelicolor A3(2))
- Intein c-terminal splicing domain-containing protein (142 kDa, Protein from Streptomyces coelicolor A3(2))
- Secreted esterase (54 kDa, Protein from Streptomyces coelicolor A3(2))
Umb1 umbrella toxin particle (local refinement of UmbB1 bound ALF of UmbC1 and UmbA1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8w22
Q-score: 0.386
Zhao Q, Bertolli S, Park YJ, Tan Y, Cutler KJ, Srinivas P, Asfahl KL, Fonesca-Garcia C, Gallagher LA, Li Y, Wang Y, Coleman-Derr D, DiMaio F, Zhang D, Peterson SB, Veesler D, Mougous JD
Nature (2024) 629 pp. 165-173 [ Pubmed: 38632398 DOI: doi:10.1038/s41586-024-07298-z ]
- Secreted protein (17 kDa, Protein from Streptomyces coelicolor A3(2))
- Umb1 umbrella toxin particle (local refinement of umbb1 bound alf of umbc1 and umba1) (Complex from Streptomyces coelicolor A3(2))
- Intein c-terminal splicing domain-containing protein (142 kDa, Protein from Streptomyces coelicolor A3(2))
- Secreted esterase (54 kDa, Protein from Streptomyces coelicolor A3(2))