CryoEM structure of human XPR1 in complex with phosphate in state A
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j51
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state B
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j52
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state C
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j53
Q-score: 0.413
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- Phosphate ion (94 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9jm0
Q-score: 0.492
Wang Y, Wang C, Guan Z, Cao J, Xu J, Wang S, Cui Y, Wang Q, Chen Y, Yin Y, Zhang D, Liu H, Sun M, Jin S, Tao P, Zou T
Cell Rep (2024) 43 pp. 114857-114857 [ Pubmed: 39395169 DOI: doi:10.1016/j.celrep.2024.114857 ]
- Rna (82-mer) (26 kDa, RNA from Escherichia coli)
- Nicotinamide (122 Da, Ligand)
- Retron ec86-effector fiber (Complex from Escherichia coli)
- [(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2r,3s,4r,5s)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate (559 Da, Ligand)
- Dna (85-mer) (26 kDa, DNA from Escherichia coli)
- Retron ec86 reverse transcriptase (37 kDa, Protein from Escherichia coli)
- Retron ec86 putative ribosyltransferase/dna-binding protein (35 kDa, Protein from Escherichia coli)
- Rna (5'-r(p*cp*gp*up*ap*ap*gp*gp*gp*up*gp*cp*gp*cp*a)-3') (4 kDa, RNA from Escherichia coli)
CryoEM structure of human XPR1 in apo state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9j4x
Q-score: 0.554
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8z9a
Q-score: 0.54
Wang Y, Qiu L, Wang B, Guan Z, Dong Z, Zhang J, Cao S, Yang L, Wang B, Gong Z, Zhang L, Ma W, Liu Z, Zhang D, Wang G, Yin P
Science (2024) 384 pp. 1453-1460 [ Pubmed: 38870272 DOI: doi:10.1126/science.adn6881 ]
- Odorant receptor, apisorco (52 kDa, Protein from Acyrthosiphon pisum)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Or-orco heterocomplex (Complex from Acyrthosiphon pisum)
- Odorant receptor, apisor5 (42 kDa, Protein from Acyrthosiphon pisum)
- [(2e)-3,7-dimethylocta-2,6-dienyl] ethanoate (196 Da, Ligand)
Cryo-EM structure of the insect olfactory receptor OR5-Orco heterocomplex from Acyrthosiphon pisum
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8z9z
Q-score: 0.448
Wang Y, Qiu L, Wang B, Guan Z, Dong Z, Zhang J, Cao S, Yang L, Wang B, Gong Z, Zhang L, Ma W, Liu Z, Zhang D, Wang G, Yin P
Science (2024) 384 pp. 1453-1460 [ Pubmed: 38870272 DOI: doi:10.1126/science.adn6881 ]
- Odorant receptor, apisorco (52 kDa, Protein from Acyrthosiphon pisum)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Odorant receptor, apisor5 (42 kDa, Protein from Acyrthosiphon pisum)
- Or-orco heterocomplex (Complex from Acyrthosiphon pisum)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8w20
Q-score: 0.295
Zhao Q, Bertolli S, Park YJ, Tan Y, Cutler KJ, Srinivas P, Asfahl KL, Fonesca-Garcia C, Gallagher LA, Li Y, Wang Y, Coleman-Derr D, DiMaio F, Zhang D, Peterson SB, Veesler D, Mougous JD
Nature (2024) 629 pp. 165-173 [ Pubmed: 38632398 DOI: doi:10.1038/s41586-024-07298-z ]
- Umb1 umbrella toxin particle (Complex from Streptomyces coelicolor A3(2))
- Secreted protein (17 kDa, Protein from Streptomyces coelicolor A3(2))
- Intein c-terminal splicing domain-containing protein (142 kDa, Protein from Streptomyces coelicolor A3(2))
- Secreted esterase (54 kDa, Protein from Streptomyces coelicolor A3(2))
Umb1 umbrella toxin particle (local refinement of UmbB1 bound ALF of UmbC1 and UmbA1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8w22
Q-score: 0.386
Zhao Q, Bertolli S, Park YJ, Tan Y, Cutler KJ, Srinivas P, Asfahl KL, Fonesca-Garcia C, Gallagher LA, Li Y, Wang Y, Coleman-Derr D, DiMaio F, Zhang D, Peterson SB, Veesler D, Mougous JD
Nature (2024) 629 pp. 165-173 [ Pubmed: 38632398 DOI: doi:10.1038/s41586-024-07298-z ]
- Secreted protein (17 kDa, Protein from Streptomyces coelicolor A3(2))
- Umb1 umbrella toxin particle (local refinement of umbb1 bound alf of umbc1 and umba1) (Complex from Streptomyces coelicolor A3(2))
- Intein c-terminal splicing domain-containing protein (142 kDa, Protein from Streptomyces coelicolor A3(2))
- Secreted esterase (54 kDa, Protein from Streptomyces coelicolor A3(2))
Cryo-EM structure of E.coli retron-Ec86 in complex with its effector at 2.5 angstrom
Resolution: 2.51 Å
EM Method: Single-particle
Fitted PDBs: 7xjg
Q-score: 0.515
Wang Y, Guan Z, Wang C, Nie Y, Chen Y, Qian Z, Cui Y, Xu H, Wang Q, Zhao F, Zhang D, Tao P, Sun M, Yin P, Jin S, Wu S, Zou T
Nat Microbiol (2022) 7 pp. 1480-1489 [ Pubmed: 35982312 DOI: doi:10.1038/s41564-022-01197-7 ]
- Retron-ec86 (rt-msdna-rna) (Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- Rna (81-mer) (25 kDa, RNA from Escherichia coli)
- Dna (105-mer) (32 kDa, DNA from Escherichia coli)
- Rna-directed dna polymerase from retron ec86 (37 kDa, Protein from Escherichia coli)
- Retron st85 family effector protein (35 kDa, Protein from Escherichia coli)
- Rna (14-mer) (4 kDa, RNA from Escherichia coli)