Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 8ix3
Q-score: 0.451
Sun H, Wang Y, Chen X, Jiang Y, Wang S, Huang Y, Liu L, Li Y, Lan M, Guo H, Yuan Q, Zhang Y, Li T, Yu H, Gu Y, Zhang J, Li S, Zheng Z, Zheng Q, Xia N
J Virol (2023) 97 pp. e0113723-e0113723 [ DOI: doi:10.1128/jvi.01137-23 Pubmed: 37855619 ]
- Nab 1g11 (Complex from Homo sapiens)
- Light chain of 1g11 (11 kDa, Protein from Homo sapiens)
- Ba.4/5 variant spike protein (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 1g11 (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 ba.4/5 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 ba.4/5 spike protein in complex with 1g11 (Complex)
Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (state 2)
Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (state 1)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7yff
Q-score: 0.445
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of GluN1a-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7yfl
Q-score: 0.404
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state.
Resolution: 6.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfo
Q-score: 0.234
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state.
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 7yfr
Q-score: 0.388
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7yfg
Q-score: 0.478
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Rat glun1-glun2c nmda receptor in complex with glycine and glutamate (Cellular component from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (97 kDa, Protein from Rattus norvegicus)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2c (87 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7yfh
Q-score: 0.535
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Rat glun1-glun2c nmda receptor in complex with glycine, glutamate and (r)-pyd-106 (Cellular component from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (97 kDa, Protein from Rattus norvegicus)
- Glycine (75 Da, Ligand)
- Methyl 4-[(2~{r})-3-ethanoyl-1-[2-(2-methyl-1~{h}-indol-3-yl)ethyl]-4-oxidanyl-5-oxidanylidene-2~{h}-pyrrol-2-yl]benzoate (432 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2c (87 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7yfi
Q-score: 0.401
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Glutamate receptor ionotropic, nmda 2c (91 kDa, Protein from Rattus norvegicus)
- Glycine (75 Da, Ligand)
- Rat tri-heteromeric glun1-glun2a-glun2c nmda receptor in complex with glycine and glutamate (Cellular component from Rattus norvegicus)
- Glutamate receptor (93 kDa, Protein from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 1 (89 kDa, Protein from Rattus norvegicus)
- Glutamic acid (147 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)