Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of enterovirus A71 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus 71 a-particle in complex with fab h1a6.2 (Complex)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of enterovirus A71 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- The fab of h1a6.2 (Complex from Mus)
- Enterovirus a71 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Coxsackievirus a16 mature virion in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp4 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (7 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Coxsackievirus a16 a-particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
Cryo-EM structure of enterovirus A71 empty particle
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of enterovirus A71 mature virion
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7yff
Q-score: 0.445
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Homo sapiens)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)