SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 7y71
Q-score: 0.415
Chia WN, Tan CW, Tan AWK, Young B, Starr TN, Lopez E, Fibriansah G, Barr J, Cheng S, Yeoh AY, Yap WC, Lim BL, Ng TS, Sia WR, Zhu F, Chen S, Zhang J, Kwek MSS, Greaney AJ, Chen M, Au GG, Paradkar PN, Peiris M, Chung AW, Bloom JD, Lye D, Lok S, Wang LF
Sci Adv (2023) 9 pp. eade3470-eade3470 [ DOI: doi:10.1126/sciadv.ade3470 Pubmed: 37494438 ]
- Fab e7 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab e7 light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (132 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein trimer complexed with fab fragment of anti-rbd antibody e7 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 4.03 Å
EM Method: Single-particle
Fitted PDBs: 7y72
Q-score: 0.395
Chia WN, Tan CW, Tan AWK, Young B, Starr TN, Lopez E, Fibriansah G, Barr J, Cheng S, Yeoh AY, Yap WC, Lim BL, Ng TS, Sia WR, Zhu F, Chen S, Zhang J, Kwek MSS, Greaney AJ, Chen M, Au GG, Paradkar PN, Peiris M, Chung AW, Bloom JD, Lye D, Lok S, Wang LF
Sci Adv (2023) 9 pp. eade3470-eade3470 [ DOI: doi:10.1126/sciadv.ade3470 Pubmed: 37494438 ]
- Spike glycoprotein (132 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein trimer complexed with fab fragment of anti-rbd antibody e7 (Complex from Homo sapiens)
- Fab e7 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab e7 light chain (23 kDa, Protein from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7yff
Q-score: 0.445
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of GluN1a-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7yfl
Q-score: 0.404
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state.
Resolution: 6.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfo
Q-score: 0.234
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state.
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 7yfr
Q-score: 0.388
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Glycine (75 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
17b10 fab in complex with full-length SARS-CoV-2 Spike G614 trimer
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8gjm
Q-score: 0.406
Kwon HJ, Zhang J, Kosikova M, Tang W, Ortega-Rodriguez U, Peng H, Meseda CA, Pedro CL, Schmeisser F, Lu J, Kang I, Zhou B, Davis CT, Wentworth DE, Chen WH, Shriver MC, Barnes RS, Pasetti MF, Weir JP, Chen B, Xie H
J Med Virol (2023) 95 pp. e28673-e28673 [ DOI: doi:10.1002/jmv.28673 Pubmed: 36916782 ]
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 17b10 fab in complex of full-length sars-cov-2 spike g614 trimer (700 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 17b10 fab (15 kDa, Protein from Mus musculus)
- Light chain of 17b10 fab (14 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
17B10 fab in complex with up-RBD of SARS-CoV-2 Spike G614 trimer
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8gjn
Q-score: 0.308
Kwon HJ, Zhang J, Kosikova M, Tang W, Ortega-Rodriguez U, Peng H, Meseda CA, Pedro CL, Schmeisser F, Lu J, Kang I, Zhou B, Davis CT, Wentworth DE, Chen WH, Shriver MC, Barnes RS, Pasetti MF, Weir JP, Chen B, Xie H
J Med Virol (2023) 95 pp. e28673-e28673 [ DOI: doi:10.1002/jmv.28673 Pubmed: 36916782 ]
- Light chain of 17b10 fab (14 kDa, Protein from Mus musculus)
- Heavy chain of 17b10 fab (15 kDa, Protein from Mus musculus)
- Spike protein s2' (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 17b10 fab in complex with up-rbd of sars-cov-2 spike g614 trimer (100 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
Structure of GluN1b-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 7yfm
Q-score: 0.309
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ DOI: doi:10.1038/s41594-023-00959-z Pubmed: 36959261 ]
- Isoform 6 of glutamate receptor ionotropic, nmda 1 (97 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7upw
Q-score: 0.464
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ DOI: doi:10.1126/sciimmunol.add5446 Pubmed: 35951767 ]
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Three rbd-down state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (650 kDa, Complex)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)