Cryo-EM structure of Ams1 bound to the FW domain of Nbr1
Resolution: 2.19 Å
EM Method: Single-particle
Fitted PDBs: 7vqo
Q-score: 0.583
Zhang J, Wang YY, Pan ZQ, Li Y, Sui J, Du LL, Ye K
Nat Commun (2022) 13 pp. 3650- [ DOI: doi:10.1038/s41467-022-31439-5 ]
- Ams1, nbr1 and male fusion protein (181 kDa, Protein from Escherichia coli K-12)
- Ams1, nbr1 and male fusion protein (520 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Zinc ion (65 Da, Ligand)
- Water (18 Da, Ligand)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7e9n
Q-score: 0.31
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of the sars-cov-2 s-6p with 35b5 fab(1 down rbd, state1) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7enf
Q-score: 0.485
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Light chain of fab30 (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of sars-cov-2 spike glycoprotein and fab30 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab30 (Complex)
- Heavy chain of fab30 (24 kDa, Protein from Homo sapiens)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7e9p
Q-score: 0.463
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 35b5 fab (Complex)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
Resolution: 4.79 Å
EM Method: Single-particle
Fitted PDBs: 7f46
Q-score: 0.114
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- 35b5 fab (Complex)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state1) (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(3 up RBDs, state2)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7e9o
Q-score: 0.381
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 35b5 fab (Complex)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3)
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7e9q
Q-score: 0.36
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- 35b5 fab (Complex)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/CPP bound state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7eoq
Q-score: 0.288
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ DOI: doi:10.1016/j.neuron.2021.05.031 Pubmed: 34186027 ]
- Structure of the human glun1/glun2a nmda receptor in the glycine/cpp bound state (Complex from Homo sapiens)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901 bound state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7eor
Q-score: 0.284
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ DOI: doi:10.1016/j.neuron.2021.05.031 Pubmed: 34186027 ]
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate/gne-6901 bound state (Complex from Homo sapiens)
- 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{r},2~{r})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one (360 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate bound state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7eos
Q-score: 0.306
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ DOI: doi:10.1016/j.neuron.2021.05.031 Pubmed: 34186027 ]
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate bound state (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)