Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 mature virion
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 8kci
Q-score: 0.356
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Atp-bound hmrp5 outward-open (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Atp-binding cassette sub-family c member 5 (160 kDa, Protein from Homo sapiens)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8j6o
Q-score: 0.403
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X, Lu Y, Li M, Lin M, Gong J, Jiang D
Nat Struct Mol Biol (2024) 31 pp. 1095-1104 [ DOI: doi:10.1038/s41594-024-01276-9 Pubmed: 38664565 ]
- Green fluorescent protein (fragment),sid1 transmembrane family member 2 (124 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- T2 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
Resolution: 3.71 Å
EM Method: Single-particle
Fitted PDBs: 8hke
Q-score: 0.431
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X, Lu Y, Li M, Lin M, Gong J, Jiang D
Nat Struct Mol Biol (2024) 31 pp. 1095-1104 [ DOI: doi:10.1038/s41594-024-01276-9 Pubmed: 38664565 ]
- Systemic rna interference defective protein 1 (88 kDa, Protein from Homo sapiens)
- Dsrna transporter (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna (37-mer) (11 kDa, RNA from Homo sapiens)
- Rna (37-mer) (11 kDa, RNA from Homo sapiens)
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7wp8
Q-score: 0.441
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk1628x in complex with three neutralizing antibodies (Complex from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2b4 light chain (12 kDa, Protein from Mus musculus)
- Spike protein stfk1628x (Complex)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2b4 heavy chain (13 kDa, Protein from Mus musculus)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 7wp6
Q-score: 0.438
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- 36h6 light chain (12 kDa, Protein from Mus musculus)
- Spike protein stfk (Complex)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 36h6 heavy chain (13 kDa, Protein from Mus musculus)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk in complex with three neutralizing antibodies (Complex from Mus musculus)
cryo-EM structure of hemoglobin
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xgy
Q-score: 0.407
Zheng L, Liu N, Gao X, Zhu W, Liu K, Wu C, Yan R, Zhang J, Gao X, Yao Y, Deng B, Xu J, Lu Y, Liu Z, Li M, Wei X, Wang HW, Peng H
Nat Methods (2023) 20 pp. 123-130 [ DOI: doi:10.1038/s41592-022-01693-y Pubmed: 36522503 ]
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Hemoglobin (Complex from Homo sapiens)
- Hemoglobin subunit beta (16 kDa, Protein from Homo sapiens)
- Hemoglobin subunit alpha (15 kDa, Protein from Homo sapiens)
Cryo-EM structure of a class T GPCR in active state
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 7xp6
Q-score: 0.415
Xu W, Wu L, Liu S, Liu X, Cao X, Zhou C, Zhang J, Fu Y, Guo Y, Wu Y, Tan Q, Wang L, Liu J, Jiang L, Fan Z, Pei Y, Yu J, Cheng J, Zhao S, Hao X, Liu ZJ, Hua T
Science (2022) 377 pp. 1298-1304 [ Pubmed: 36108005 DOI: doi:10.1126/science.abo1633 ]
- Strychnine (334 Da, Ligand)
- Guanine nucleotide-binding protein g(t) subunit alpha-3 (30 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Complex of gpcr and g protein (Complex from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Endoglucanase h,taste receptor type 2 member 46,endoglucanase h,taste receptor type 2 member 46,bitter taste receptor t2r46 (91 kDa, Protein from Homo sapiens)
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 2E6 (CVB1-M:2E6)
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 7x2o
Q-score: 0.591
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ DOI: doi:10.1016/j.chom.2022.08.001 Pubmed: 36002016 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Palmitic acid (256 Da, Ligand)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 mature virion in complex with nab 2e6 (cvb1-m:2e6) (Complex from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- 2e6 light chain (11 kDa, Protein from Mus musculus)