Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of enterovirus A71 mature virion
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 (Virus from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
Cryo-EM structure of Coxsackievirus B1 mature virion
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7dpf
Q-score: 0.601
Xu L, Zheng Q, Zhu R, Yin Z, Yu H, Lin Y, Wu Y, He M, Huang Y, Jiang Y, Sun H, Zha Z, Yang H, Huang Q, Zhang D, Chen Z, Ye X, Han J, Yang L, Liu C, Que Y, Fang M, Gu Y, Zhang J, Luo W, Zhou ZH, Li S, Cheng T, Xia N
Cell Host Microbe (2021) 29 pp. 448-462.e5 [ DOI: doi:10.1016/j.chom.2021.01.001 Pubmed: 33539764 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- Palmitic acid (256 Da, Ligand)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 5F5
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7dq7
Q-score: 0.565
Xu L, Zheng Q, Zhu R, Yin Z, Yu H, Lin Y, Wu Y, He M, Huang Y, Jiang Y, Sun H, Zha Z, Yang H, Huang Q, Zhang D, Chen Z, Ye X, Han J, Yang L, Liu C, Que Y, Fang M, Gu Y, Zhang J, Luo W, Zhou ZH, Li S, Cheng T, Xia N
Cell Host Microbe (2021) 29 pp. 448-462.e5 [ DOI: doi:10.1016/j.chom.2021.01.001 Pubmed: 33539764 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 5f5 vl (11 kDa, Protein from Mus musculus)
- Palmitic acid (256 Da, Ligand)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Nab 5f5 (Complex from Mus musculus)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 complex with nab 5f5 (Complex)
- 5f5 vh (13 kDa, Protein from Mus musculus)
- Coxsackievirus b1 (Complex from Coxsackievirus B1)
The cryo-EM structure of coxsackievirus A16 mature virion
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 6lha
Q-score: 0.504
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Vp4 protein (7 kDa, Protein from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Vp3 protein (26 kDa, Protein from Coxsackievirus A16)
- Vp2 protein (27 kDa, Protein from Coxsackievirus A16)
- Vp1 protein (33 kDa, Protein from Coxsackievirus A16)
The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 18A7
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 6lhk
Q-score: 0.634
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Vp4 protein (7 kDa, Protein from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Vp3 protein (26 kDa, Protein from Coxsackievirus A16)
- Vp2 protein (27 kDa, Protein from Coxsackievirus A16)
- Vp1 protein (33 kDa, Protein from Coxsackievirus A16)
The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 14B10
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6lhp
Q-score: 0.553
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Heavy chain variable region of fab 14b10 (12 kDa, Protein from Mus musculus)
- Light chain variable region of fab 14b10 (11 kDa, Protein from Mus musculus)
- Fab antibody (Complex from Mus musculus)
- Coxsackievirus a16 complex (Complex)
- Vp4 protein (7 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Complex from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Vp3 protein (26 kDa, Protein from Coxsackievirus A16)
- Vp2 protein (27 kDa, Protein from Coxsackievirus A16)
- Vp1 protein (33 kDa, Protein from Coxsackievirus A16)
The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab NA9D7
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 6lhq
Q-score: 0.549
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Fab na9d7 (Complex from Mus musculus)
- Vp3 protein (26 kDa, Protein from Coxsackievirus A16)
- Vp4 protein (7 kDa, Protein from Coxsackievirus A16)
- Heavy chain variable region of fab na9d7 (13 kDa, Protein from Mus musculus)
- Coxsackievirus a16 (Complex from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Coxsackievirus a16 complex with fab na9d7 (Complex)
- Light chain variable region of fab na9d7 (11 kDa, Protein from Mus musculus)
- Vp2 protein (27 kDa, Protein from Coxsackievirus A16)
- Vp1 protein (33 kDa, Protein from Coxsackievirus A16)
Localized reconstruction of coxsackievirus A16 mature virion in complex with Fab 18A7
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 6lht
Q-score: 0.477
He M, Xu L, Zheng Q, Zhu R, Yin Z, Zha Z, Lin Y, Yang L, Huang Y, Ye X, Li S, Hou W, Wu Y, Han J, Liu D, Li Z, Chen Z, Yu H, Que Y, Wang Y, Yan X, Zhang J, Gu Y, Zhou ZH, Cheng T, Li S, Xia N
Cell Host Microbe (2020) 27 pp. 249- [ Pubmed: 32027857 DOI: doi:10.1016/j.chom.2020.01.003 ]
- Light chain variable region of fab 18a7 (12 kDa, Protein from Mus musculus)
- Coxsackievirus a16 in complex with fab 18a7 (Complex)
- Fab 18a7 (Complex from Mus musculus)
- Heavy chain variable region of fab 18a7 (13 kDa, Protein from Mus musculus)
- Coxsackievirus a16 (Complex from Coxsackievirus A16)
- Sphingosine (299 Da, Ligand)
- Vp1 protein (33 kDa, Protein from Coxsackievirus A16)