Cryo-EM structure of enterovirus A71 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus a71 mature virion in complex with fab h1a6.2 (Complex)
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of enterovirus A71 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Enterovirus 71 a-particle in complex with fab h1a6.2 (Complex)
- Fab h1a6.2 (Complex from Mus)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of enterovirus A71 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- The fab of h1a6.2 (Complex from Mus)
- Enterovirus a71 empty particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Coxsackievirus a16 mature virion in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp4 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (7 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Coxsackievirus a16 a-particle in complex with fab h1a6.2 (Complex)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- The fab of h1a6.2 (Complex from Mus)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
Cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab h1A6.2 (local refinement)
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- The fab of h1a6.2 (Complex from Mus musculus)
- Genome polyprotein (27 kDa, Protein from Coxsackievirus A16)
- Coxsackievirus a16 (Virus from Coxsackievirus A16)
- Genome polyprotein (26 kDa, Protein from Coxsackievirus A16)
- Capsid protein vp1 (33 kDa, Protein from Coxsackievirus A16)
- The light chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- The heavy chain of fab h1a6.2 (12 kDa, Protein from Mus musculus)
- Coxsackievirus a16 empty particle in complex with fab h1a6.2 (Complex)
Cryo-EM structure of enterovirus A71 empty particle
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Cryo-EM structure of enterovirus A71 mature virion
Zhu R, Wu Y, Huang Y, Jiang Y, Jiang Y, Zhang D, Sun H, Zhou Z, Zhou L, Weng S, Chen H, Chen X, Ning W, Zou Y, He M, Yang H, Deng W, Li Y, Chen Z, Ye X, Han J, Yin Z, Zhao H, Liu C, Que Y, Fang M, Yu H, Zhang J, Luo W, Li S, Zheng Q, Xu L, Xia N, Cheng T
Nat Microbiol (2024) 9 pp. 2939-2953 [ Pubmed: 39424982 DOI: doi:10.1038/s41564-024-01822-7 ]
- Capsid protein vp4 (7 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Capsid protein vp2 (27 kDa, Protein from Enterovirus A71)
- Capsid protein vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 8iwh
Q-score: 0.541
Feng Y, Li Z, Li X, Shen L, Liu X, Zhou C, Zhang J, Sang M, Han G, Yang W, Kuang T, Wang W, Shen JR
Sci Adv (2023) 9 pp. eadi8446-eadi8446 [ DOI: doi:10.1126/sciadv.adi8446 Pubmed: 37878698 ]
- (3s,3'r,5r,6s,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol (582 Da, Ligand)
- Fe (ii) ion (55 Da, Ligand)
- Photosystem ii cp47 reaction center protein (56 kDa, Protein from Thalassiosira pseudonana)
- Cytochrome b559 subunit beta (4 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii protein d1 (36 kDa, Protein from Thalassiosira pseudonana)
- Fucoxanthin chlorophyll a/c light-harvesting protein, major type (20 kDa, Protein from Thalassiosira pseudonana)
- Fucoxanthin chlorophyll a/c protein 5 (21 kDa, Protein from Thalassiosira pseudonana)
- Ca-mn4-o5 cluster (339 Da, Ligand)
- Dodecyl-alpha-d-maltoside (510 Da, Ligand)
- (1~{r})-3,5,5-trimethyl-4-[(1~{e},3~{e},5~{e},7~{e},9~{e},11~{e},13~{e},15~{e})-3,7,12,16-tetramethyl-18-[(4~{r})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15-octaen-17-ynyl]cyclohex-3-en-1-ol (566 Da, Ligand)
- Chlorophyll a (893 Da, Ligand)
- Ps ii complex 12 kda extrinsic protein (15 kDa, Protein from Thalassiosira pseudonana)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Photosystem ii subunit, psbn. (2 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii reaction center protein j (4 kDa, Protein from Thalassiosira pseudonana)
- Bicarbonate ion (61 Da, Ligand)
- Fucoxanthin chl a/c protein, lhca clade (24 kDa, Protein from Thalassiosira pseudonana)
- 2,3-dimethyl-5-(3,7,11,15,19,23,27,31,35-nonamethyl-2,6,10,14,18,22,26,30,34-hexatriacontanonaenyl-2,5-cyclohexadiene-1,4-dione-2,3-dimethyl-5-solanesyl-1,4-benzoquinone (749 Da, Ligand)
- Beta-carotene (536 Da, Ligand)
- Photosystem ii reaction center protein t (3 kDa, Protein from Thalassiosira pseudonana)
- Fucoxanthin-chlorophyll a-c binding protein, plastid (21 kDa, Protein from Thalassiosira pseudonana)
- Oxygen-evolving enhancer protein 1 (32 kDa, Protein from Thalassiosira pseudonana)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- (3s,3's,5r,5'r,6s,6'r,8'r)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate (658 Da, Ligand)
- Photosystem ii reaction center protein h (7 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii reaction center protein l (4 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii reaction center m protein, plastid (12 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii reaction center protein z (6 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii subunit, psbw (6 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii reaction center protein i (3 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii cp43 reaction center protein (51 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii reaction center protein k (4 kDa, Protein from Thalassiosira pseudonana)
- Fucoxanthin chlorophyll a/c protein-li818 clade (21 kDa, Protein from Thalassiosira pseudonana)
- Chloride ion (35 Da, Ligand)
- Photosystem ii reaction center protein ycf12 (3 kDa, Protein from Thalassiosira pseudonana)
- Chlorophyll c1 (610 Da, Ligand)
- Chlorophyll c2 (608 Da, Ligand)
- Photosystem ii psb31 protein domain-containing protein (18 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii d2 protein (39 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii subunit, psbq. (22 kDa, Protein from Thalassiosira pseudonana)
- Photosystem ii reaction center x protein (3 kDa, Protein from Thalassiosira pseudonana)
- Cytochrome c-550 (17 kDa, Protein from Thalassiosira pseudonana)
- Fucoxanthin chlorophyll a/c protein 6 (20 kDa, Protein from Thalassiosira pseudonana)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Structure of psii-fcpii supercomplex containing monomeric lhcx and dimeric fcpii from thalassiosira pseudonana (Complex from Thalassiosira pseudonana)
- Pheophytin a (871 Da, Ligand)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Cytochrome b559 subunit alpha (9 kDa, Protein from Thalassiosira pseudonana)