momSalB bound Kappa Opioid Receptor in complex with Gi1
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 8dzp
Q-score: 0.533
Han J, Zhang J, Nazarova AL, Bernhard SM, Krumm BE, Zhao L, Lam JH, Rangari VA, Majumdar S, Nichols DE, Katritch V, Yuan P, Fay JF, Che T
Nature (2023) 617 pp. 417-425 [ DOI: doi:10.1038/s41586-023-06030-7 Pubmed: 37138078 ]
- Momsalb bound kappa opioid receptor in complex with gi1 (Complex from Homo sapiens)
- Methyl (2s,4ar,6ar,7r,9s,10as,10br)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxododecahydro-2h-naphtho[2,1-c]pyran-7-carboxylate (434 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 protein (26 kDa, Protein from Mus musculus)
- Kappa-type opioid receptor (34 kDa, Protein from Homo sapiens)
momSalB bound Kappa Opioid Receptor in complex with GoA
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 8dzq
Q-score: 0.459
Han J, Zhang J, Nazarova AL, Bernhard SM, Krumm BE, Zhao L, Lam JH, Rangari VA, Majumdar S, Nichols DE, Katritch V, Yuan P, Fay JF, Che T
Nature (2023) 617 pp. 417-425 [ DOI: doi:10.1038/s41586-023-06030-7 Pubmed: 37138078 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Methyl (2s,4ar,6ar,7r,9s,10as,10br)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxododecahydro-2h-naphtho[2,1-c]pyran-7-carboxylate (434 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Momsalb bound kappa opioid receptor in complex with goa (Complex from Homo sapiens)
- Scfv16 protein (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(o) subunit alpha (40 kDa, Protein from Homo sapiens)
- Kappa-type opioid receptor (34 kDa, Protein from Homo sapiens)
GR89,696 bound Kappa Opioid Receptor in complex with gustducin
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8dzr
Q-score: 0.485
Han J, Zhang J, Nazarova AL, Bernhard SM, Krumm BE, Zhao L, Lam JH, Rangari VA, Majumdar S, Nichols DE, Katritch V, Yuan P, Fay JF, Che T
Nature (2023) 617 pp. 417-425 [ DOI: doi:10.1038/s41586-023-06030-7 Pubmed: 37138078 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Methyl (3r)-4-[(3,4-dichlorophenyl)acetyl]-3-[(pyrrolidin-1-yl)methyl]piperazine-1-carboxylate (414 Da, Ligand)
- Kappa-type opioid receptor (32 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Gr89,696 bound kappa opioid receptor in complex with gustducin (Complex from Homo sapiens)
- G alpha gustducin protein (40 kDa, Protein from Homo sapiens)
- Scfv16 protein (26 kDa, Protein from Mus musculus)
GR89,696 bound Kappa Opioid Receptor in complex with Gz
Resolution: 2.65 Å
EM Method: Single-particle
Fitted PDBs: 8dzs
Q-score: 0.531
Han J, Zhang J, Nazarova AL, Bernhard SM, Krumm BE, Zhao L, Lam JH, Rangari VA, Majumdar S, Nichols DE, Katritch V, Yuan P, Fay JF, Che T
Nature (2023) 617 pp. 417-425 [ DOI: doi:10.1038/s41586-023-06030-7 Pubmed: 37138078 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Methyl (3r)-4-[(3,4-dichlorophenyl)acetyl]-3-[(pyrrolidin-1-yl)methyl]piperazine-1-carboxylate (414 Da, Ligand)
- Guanine nucleotide-binding protein g(z) subunit alpha (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 protein (26 kDa, Protein from Mus musculus)
- Kappa-type opioid receptor (34 kDa, Protein from Homo sapiens)
- Gr89,696 bound kappa opioid receptor in complex with gz (Complex from Homo sapiens)