Cryo-EM structure of partial VP4 from simian rotavirus SA11
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 8ygr
Q-score: 0.413
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Partial vp4 of rotavirus (Complex from Rotavirus A)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Rotavirus a (Virus from Rotavirus A)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8ygs
Q-score: 0.444
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Immune complex of rotavirus with 7h13 (Complex from Rotavirus A)
- Fab 7h13 (Complex from Mus musculus)
- Antibody 7h13 heavy chain (12 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Antibody 7h13 light chain (11 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13-I54G mutant (left side)
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8ygt
Q-score: 0.559
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Immune complex of rotavirus with 7h13 (Complex from Rotavirus A)
- Fab 7h13 (Complex from Mus musculus)
- Antibody 7h13-i54g mutant heavy chain (12 kDa, Protein from Mus musculus)
- Antibody 7h13-i54g mutant light chain (11 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13-I54G mutant (right side)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8ygu
Q-score: 0.526
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Outer capsid protein vp4 (87 kDa, Protein from Rotavirus A)
- Immune complex of rotavirus with 7h13-i54g mutant (Complex from Rotavirus A)
- Fab 7h13 (Complex from Rotavirus A)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Antibody 7h13-i54g mutant light chain (11 kDa, Protein from Mus musculus)
- Antibody 7h13-i54g mutant heavy chain (12 kDa, Protein from Mus musculus)
Structure of the extracellular domain of Protein Sevenless
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 9bhx
Q-score: 0.36
Zhang J, Tsutsui Y, Li H, Li T, Wang Y, Laraki S, Alarcon-Frias S, Stayrook SE, Klein DE
Nat Commun (2025) 16 pp. 808-808 [ DOI: doi:10.1038/s41467-025-55943-6 Pubmed: 39827240 ]
- Protein sevenless (181 kDa, Protein from Drosophila melanogaster)
- Protein sevenless (Cell from Drosophila melanogaster)
Integrin alpha-v beta-8 in complex with the Fab of 130H2
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 9ind
Q-score: 0.533
Guo C, Sun H, Du Y, Dai X, Pang Y, Han Z, Xiong X, Li S, Zhang J, Zheng Q, Gui X
J Exp Clin Cancer Res (2025) 44 pp. 1-1 [ DOI: doi:10.1186/s13046-024-03250-1 Pubmed: 39743547 ]
- Integrin alpha-v beta-8 complexed with antibody fab fragment of 130h2 (Complex)
- Integrin beta-8 (39 kDa, Protein from Homo sapiens)
- 130h2-fab (Complex from Mus musculus)
- The light chain of 130h2-fab (11 kDa, Protein from Mus musculus)
- Integrin alpha-v beta-8 (Complex from Homo)
- Integrin alpha-v heavy chain (47 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of 130h2-fab (13 kDa, Protein from Mus musculus)
CryoEM structure of compound HNC-1664 bound with RdRP-RNA complex of SARS-CoV-2
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8xko
Q-score: 0.486
Jia X, Jing X, Li M, Gao M, Zhong Y, Li E, Liu Y, Li R, Yao G, Liu Q, Zhou M, Hou Y, An L, Hong Y, Li S, Zhang J, Wang W, Zhang K, Gong P, Chiu S
Nat Commun (2024) 15 pp. 10750-10750 [ Pubmed: 39737930 DOI: doi:10.1038/s41467-024-54918-3 ]
- Rna (5'-r(p*up*up*cp*ap*up*gp*cp*up*ap*cp*gp*cp*gp*up*ap*g)-3') (5 kDa, RNA from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- Non-structural protein 7 (10 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Rna (5'-r(p*cp*up*ap*cp*gp*cp*gp*up*ap*gp*cp*ap*up*g)-3') (4 kDa, RNA from synthetic construct)
- Cryoem structure of compound hnc-1644 bound with rdrp-rna (150 kDa, Complex from Severe acute respiratory syndrome coronavirus)
- [[(2~{r},3~{r},4~{s},5~{r})-4-fluoranyl-5-(5-iodanyl-4-methyl-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (633 Da, Ligand)
- Rna-directed rna polymerase nsp12 (108 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus)
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 8xpo
Q-score: 0.554
Jia X, Jing X, Li M, Gao M, Zhong Y, Li E, Liu Y, Li R, Yao G, Liu Q, Zhou M, Hou Y, An L, Hong Y, Li S, Zhang J, Wang W, Zhang K, Gong P, Chiu S
Nat Commun (2024) 15 pp. 10750-10750 [ Pubmed: 39737930 DOI: doi:10.1038/s41467-024-54918-3 ]
- Rna (32-mer) (10 kDa, RNA from synthetic construct)
- Rna (9-mer) (2 kDa, RNA from synthetic construct)
- Rna (14-mer) (4 kDa, RNA from synthetic construct)
- Rna (Complex from synthetic construct)
- [[(2~{r},3~{r},4~{s},5~{r})-4-fluoranyl-5-(5-iodanyl-4-methyl-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate (633 Da, Ligand)
- Rna-directed rna polymerase l (255 kDa, Protein from Lassa virus Josiah)
- Lassa virus rdrp elongation complex with the ntp form of compound 13b bound in the active site (270 kDa, Complex)
- Lassa virus l protein (Complex from Lassa virus Josiah)
Complex of FMDV O/18074 and inter-serotype broadly neutralizing antibodies pOA-2
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8y0q
Q-score: 0.621
Li F, Wu S, Lv L, Huang S, Zhang Z, Zerang Z, Li P, Cao Y, Bao H, Sun P, Bai X, He Y, Fu Y, Yuan H, Ma X, Zhao Z, Zhang J, Wang J, Wang T, Li D, Zhang Q, He J, Liu Z, Lu Z, Lei D, Li K
PLoS Pathog (2024) 20 pp. e1012623-e1012623 [ DOI: doi:10.1371/journal.ppat.1012623 Pubmed: 39405339 ]
- Inter-serotype broadly neutralizing antibodies poa-2 (Complex from Sus scrofa)
- Complex of fmdv o/18074 and inter-serotype broadly neutralizing antibodies poa-2 (Complex)
- Vp3 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus O)
- Vp1 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus O)
- Vp4 of capsid protein (8 kDa, Protein from Foot-and-mouth disease virus O)
- Poa2 vl (11 kDa, Protein from Sus scrofa)
- Vp2 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus O)
- Fmdv o/18074 (Complex from Foot-and-mouth disease virus O)
- Poa2 vh (13 kDa, Protein from Sus scrofa)
Complex of FMDV A/WH/CHA/09 and inter-serotype broadly neutralizing antibodies pOA-2
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8y0r
Q-score: 0.578
Li F, Wu S, Lv L, Huang S, Zhang Z, Zerang Z, Li P, Cao Y, Bao H, Sun P, Bai X, He Y, Fu Y, Yuan H, Ma X, Zhao Z, Zhang J, Wang J, Wang T, Li D, Zhang Q, He J, Liu Z, Lu Z, Lei D, Li K
PLoS Pathog (2024) 20 pp. e1012623-e1012623 [ DOI: doi:10.1371/journal.ppat.1012623 Pubmed: 39405339 ]
- Inter-serotype broadly neutralizing antibodies poa-2 (Complex from Sus scrofa)
- Complex of fmdv a/wh/cha/09 and inter-serotype broadly neutralizing antibodies poa-2 (Complex)
- Vp2 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus A)
- Vp3 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus A)
- Fmdv a/wh/cha/09 (Complex from Foot-and-mouth disease virus A)
- Vp4 of capsid protein (8 kDa, Protein from Foot-and-mouth disease virus A)
- Vp1 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus A)
- Poa2 vl (11 kDa, Protein from Sus scrofa)
- Poa2 vh (13 kDa, Protein from Sus scrofa)