Allosteric regulation of nitrate transporter NRT via the signalling protein PII
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8w9m
Q-score: 0.556
Li B, Wang XQ, Li QY, Xu D, Li J, Hou WT, Chen Y, Jiang YL, Zhou CZ
PNAS (2024) 121 pp. e2318320121-e2318320121 [ Pubmed: 38457518 DOI: doi:10.1073/pnas.2318320121 ]
- Nitrate transporter nrtbcd complexed with atp (Complex from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport permease protein (30 kDa, Protein from Nostoc sp. PCC 7120 = FACHB-418)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nitrate transport atp-binding protein (31 kDa, Protein from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport atp-binding protein (76 kDa, Protein from Nostoc sp. PCC 7120 = FACHB-418)
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wm7
Q-score: 0.475
Li B, Wang XQ, Li QY, Xu D, Li J, Hou WT, Chen Y, Jiang YL, Zhou CZ
PNAS (2024) 121 pp. e2318320121-e2318320121 [ Pubmed: 38457518 DOI: doi:10.1073/pnas.2318320121 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nitrogen regulatory protein p-ii (13 kDa, Protein from Nostoc sp.)
- Nitrate transport permease protein (30 kDa, Protein from Nostoc sp.)
- Complex of nitrate transporter nrtbcd with signling protein pii (Complex from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport atp-binding protein (31 kDa, Protein from Nostoc sp.)
- Nitrate transport atp-binding protein (76 kDa, Protein from Nostoc sp.)
Cryo-EM structure of cyanobacterial nitrate/nitrite transporter NrtBCD in complex with nitrate
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8wm8
Q-score: 0.463
Li B, Wang XQ, Li QY, Xu D, Li J, Hou WT, Chen Y, Jiang YL, Zhou CZ
PNAS (2024) 121 pp. e2318320121-e2318320121 [ Pubmed: 38457518 DOI: doi:10.1073/pnas.2318320121 ]
- Complex of nitrate transporter nrtbcd with nitrate (Complex from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport permease protein (30 kDa, Protein from Nostoc sp.)
- Nitrate transport atp-binding protein (31 kDa, Protein from Nostoc sp.)
- Nitrate transport atp-binding protein (76 kDa, Protein from Nostoc sp.)
- Nitrate ion (62 Da, Ligand)
Cryo-EM structure of SIDT1 in complex with phosphatidic acid
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8jul
Q-score: 0.55
Sun CR, Xu D, Yang F, Hou Z, Luo Y, Zhang CY, Shan G, Huang G, Yao X, Chen Y, Li Q, Zhou CZ
Cell Res (2024) 34 pp. 84-87 [ DOI: doi:10.1038/s41422-023-00889-x Pubmed: 37932444 ]
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of sidt1 in complex with phosphatidic acid (Complex from Homo sapiens)
- Sid1 transmembrane family member 1 (93 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Cryo-EM structure of SIDT1 E555Q mutant
Resolution: 2.38 Å
EM Method: Single-particle
Fitted PDBs: 8jun
Q-score: 0.574
Sun CR, Xu D, Yang F, Hou Z, Luo Y, Zhang CY, Shan G, Huang G, Yao X, Chen Y, Li Q, Zhou CZ
Cell Res (2024) 34 pp. 84-87 [ DOI: doi:10.1038/s41422-023-00889-x Pubmed: 37932444 ]
- Cryo-em structure of sidt1 e555q mutant (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sid1 transmembrane family member 1 (93 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
huamn bile salt exporter ABCB11 with N-terminal truncated
Wang L, Hou WT, Wang J, Xu D, Guo C, Sun L, Ruan K, Zhou CZ, Chen Y
Cell Res (2022) 32 pp. 501-504 [ DOI: doi:10.1038/s41422-021-00611-9 Pubmed: 35043010 ]
- Abcb11 (Cellular component from Homo sapiens)
- Human abcb11 (Protein from Homo sapiens)
Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7fdv
Q-score: 0.528
Xu D, Li Y, Yang F, Sun CR, Pan J, Wang L, Chen ZP, Fang SC, Yao X, Hou WT, Zhou CZ, Chen Y
Cell Rep (2022) 38 pp. 110298-110298 [ Pubmed: 35081353 DOI: doi:10.1016/j.celrep.2022.110298 ]
- The complex of human abcg1 with cholesterol and atp (152 kDa, Complex from Homo sapiens)
- [(e,2s,3r)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate (703 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Atp-binding cassette sub-family g member 1 (75 kDa, Protein from Homo sapiens)
Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1
Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vx8
Q-score: 0.594
Chen ZP, Xu D, Wang L, Mao YX, Li Y, Cheng MT, Zhou CZ, Hou WT, Chen Y
Nat Commun (2022) 13 pp. 3299-3299 [ DOI: doi:10.1038/s41467-022-30974-5 Pubmed: 35676282 ]
- Atp-bound human peroxisomal abcd1 (175 MDa, Complex from Caenorhabditis elegans)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Peroxisomal membrane protein related,atp-binding cassette sub-family d member 1 (87 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 7vzb
Q-score: 0.429
Chen ZP, Xu D, Wang L, Mao YX, Li Y, Cheng MT, Zhou CZ, Hou WT, Chen Y
Nat Commun (2022) 13 pp. 3299-3299 [ DOI: doi:10.1038/s41467-022-30974-5 Pubmed: 35676282 ]
- Cholesterol hemisuccinate (486 Da, Ligand)
- Human peroxisomal abcd1 (175 MDa, Cellular component from Caenorhabditis elegans)
- Peroxisomal membrane protein related,atp-binding cassette sub-family d member 1 (87 kDa, Protein from Homo sapiens)
- S-[2-[3-[[(2r)-4-[[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate (1 kDa, Ligand)