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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Zhou CZ" AND citation_journal_name:"NAT CARDIOVASC RES"

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EMD-35167

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Cryo-EM structure of dipyridamole-bound ABCC4

Release date: May 24, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8i4a
Q-score: 0.455

Chen Y, Wang L, Hou WT, Zhou CZ, Chen Y, Li Q

Nat Cardiovasc Res (2023) [ ]

Sample:

Atp-binding cassette sub-family c member 4 (149 kDa, Protein from Homo sapiens)
Dipyridamole-bound abcc4 (Complex from Homo sapiens)
2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol (504 Da, Ligand)

EMD-35168

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Cryo-EM structure of apo-form ABCC4

Release date: May 24, 2023
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8i4b
Q-score: 0.426

Chen Y, Wang L, Hou WT, Zhou CZ, Chen Y, Li Q

Nat Cardiovasc Res (2023) [ ]

Sample:

Apo-form abcc4 (Complex from Homo sapiens)
Atp-binding cassette sub-family c member 4 (149 kDa, Protein from Homo sapiens)

EMD-35169

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Cryo-EM structure of U46619-bound ABCC4

Release date: May 24, 2023
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 8i4c
Q-score: 0.301

Chen Y, Wang L, Hou WT, Zhou CZ, Chen Y, Li Q

Nat Cardiovasc Res (2023) [ ]

Sample:

Atp-binding cassette sub-family c member 4 (149 kDa, Protein from Homo sapiens)
(5z)-7-{(1r,4s,5s,6r)-6-[(1e,3s)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (350 Da, Ligand)
Cryo-em structure of u46619-bound abcc4 (Complex from Homo sapiens)

EMD-35967

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Cryo-EM structure of aspirin-bound ABCC4

Release date: May 24, 2023
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8j3w
Q-score: 0.413

Chen Y, Wang L, Hou WT, Zhou CZ, Chen Y, Li Q

Nat Cardiovasc Res (2023) [ ]

Sample:

Apo-form abcc4 (Complex from Homo sapiens)
Atp-binding cassette sub-family c member 4 (149 kDa, Protein from Homo sapiens)
2-(acetyloxy)benzoic acid (180 Da, Ligand)

EMD-35968

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Cryo-EM structure of ATP-U46619-bound ABCC4

Release date: May 24, 2023
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 8j3z
Q-score: 0.455

Chen Y, Wang L, Hou WT, Zhou CZ, Chen Y, Li Q

Nat Cardiovasc Res (2023) [ ]

Sample:

Atp-binding cassette sub-family c member 4 (149 kDa, Protein from Homo sapiens)
(5z)-7-{(1r,4s,5s,6r)-6-[(1e,3s)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (350 Da, Ligand)
Apo-form abcc4 (Complex from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
Magnesium ion (24 Da, Ligand)

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Showing 1 - 5 of 5. Page 1 of 1

Display: Statistics

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EMDB [5]

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