Allosteric regulation of nitrate transporter NRT via the signalling protein PII
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8w9m
Q-score: 0.556
Li B, Wang XQ, Li QY, Xu D, Li J, Hou WT, Chen Y, Jiang YL, Zhou CZ
PNAS (2024) 121 pp. e2318320121-e2318320121 [ Pubmed: 38457518 DOI: doi:10.1073/pnas.2318320121 ]
- Nitrate transporter nrtbcd complexed with atp (Complex from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport permease protein (30 kDa, Protein from Nostoc sp. PCC 7120 = FACHB-418)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nitrate transport atp-binding protein (31 kDa, Protein from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport atp-binding protein (76 kDa, Protein from Nostoc sp. PCC 7120 = FACHB-418)
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wm7
Q-score: 0.475
Li B, Wang XQ, Li QY, Xu D, Li J, Hou WT, Chen Y, Jiang YL, Zhou CZ
PNAS (2024) 121 pp. e2318320121-e2318320121 [ Pubmed: 38457518 DOI: doi:10.1073/pnas.2318320121 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nitrogen regulatory protein p-ii (13 kDa, Protein from Nostoc sp.)
- Nitrate transport permease protein (30 kDa, Protein from Nostoc sp.)
- Complex of nitrate transporter nrtbcd with signling protein pii (Complex from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport atp-binding protein (31 kDa, Protein from Nostoc sp.)
- Nitrate transport atp-binding protein (76 kDa, Protein from Nostoc sp.)
Cryo-EM structure of cyanobacterial nitrate/nitrite transporter NrtBCD in complex with nitrate
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8wm8
Q-score: 0.463
Li B, Wang XQ, Li QY, Xu D, Li J, Hou WT, Chen Y, Jiang YL, Zhou CZ
PNAS (2024) 121 pp. e2318320121-e2318320121 [ Pubmed: 38457518 DOI: doi:10.1073/pnas.2318320121 ]
- Complex of nitrate transporter nrtbcd with nitrate (Complex from Nostoc sp. PCC 7120 = FACHB-418)
- Nitrate transport permease protein (30 kDa, Protein from Nostoc sp.)
- Nitrate transport atp-binding protein (31 kDa, Protein from Nostoc sp.)
- Nitrate transport atp-binding protein (76 kDa, Protein from Nostoc sp.)
- Nitrate ion (62 Da, Ligand)
Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8jxq
Q-score: 0.364
Mao YX, Chen ZP, Wang L, Wang J, Zhou CZ, Hou WT, Chen Y
Nat Commun (2024) 15 pp. 1061-1061 [ DOI: doi:10.1038/s41467-024-45337-5 Pubmed: 38316776 ]
- Atp-binding cassette sub-family c member 2 (Cellular component from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- 2-[3-[5-[(e)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1h-pyrrol-2-yl]methyl]-4-methyl-1h-pyrrol-3-yl]propanoylamino]ethanesulfonic acid (798 Da, Ligand)
- Atp-binding cassette sub-family c member 2 (176 kDa, Protein from Homo sapiens)
Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8jxu
Q-score: 0.349
Mao YX, Chen ZP, Wang L, Wang J, Zhou CZ, Hou WT, Chen Y
Nat Commun (2024) 15 pp. 1061-1061 [ DOI: doi:10.1038/s41467-024-45337-5 Pubmed: 38316776 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-binding cassette sub-family c member 2 (Cellular component from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Atp-binding cassette sub-family c member 2 (176 kDa, Protein from Homo sapiens)
Cryo-EM structure of SIDT1 in complex with phosphatidic acid
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8jul
Q-score: 0.55
Sun CR, Xu D, Yang F, Hou Z, Luo Y, Zhang CY, Shan G, Huang G, Yao X, Chen Y, Li Q, Zhou CZ
Cell Res (2024) 34 pp. 84-87 [ DOI: doi:10.1038/s41422-023-00889-x Pubmed: 37932444 ]
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Cryo-em structure of sidt1 in complex with phosphatidic acid (Complex from Homo sapiens)
- Sid1 transmembrane family member 1 (93 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
Cryo-EM structure of SIDT1 E555Q mutant
Resolution: 2.38 Å
EM Method: Single-particle
Fitted PDBs: 8jun
Q-score: 0.574
Sun CR, Xu D, Yang F, Hou Z, Luo Y, Zhang CY, Shan G, Huang G, Yao X, Chen Y, Li Q, Zhou CZ
Cell Res (2024) 34 pp. 84-87 [ DOI: doi:10.1038/s41422-023-00889-x Pubmed: 37932444 ]
- Cryo-em structure of sidt1 e555q mutant (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sid1 transmembrane family member 1 (93 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs