Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs
Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1
Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7vx8
Q-score: 0.594
Chen ZP, Xu D, Wang L, Mao YX, Li Y, Cheng MT, Zhou CZ, Hou WT, Chen Y
Nat Commun (2022) 13 pp. 3299-3299 [ DOI: doi:10.1038/s41467-022-30974-5 Pubmed: 35676282 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Atp-bound human peroxisomal abcd1 (175 MDa, Complex from Caenorhabditis elegans)
- Magnesium ion (24 Da, Ligand)
- Peroxisomal membrane protein related,atp-binding cassette sub-family d member 1 (87 kDa, Protein from Homo sapiens)
Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 7vzb
Q-score: 0.429
Chen ZP, Xu D, Wang L, Mao YX, Li Y, Cheng MT, Zhou CZ, Hou WT, Chen Y
Nat Commun (2022) 13 pp. 3299-3299 [ DOI: doi:10.1038/s41467-022-30974-5 Pubmed: 35676282 ]
- Cholesterol hemisuccinate (486 Da, Ligand)
- S-[2-[3-[[(2r)-4-[[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate (1 kDa, Ligand)
- Peroxisomal membrane protein related,atp-binding cassette sub-family d member 1 (87 kDa, Protein from Homo sapiens)
- Human peroxisomal abcd1 (175 MDa, Cellular component from Caenorhabditis elegans)
Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50B in the auto-inhibited E2P state
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 7vgh
Q-score: 0.522
Cheng MT, Chen Y, Chen ZP, Liu X, Zhang Z, Chen Y, Hou WT, Zhou CZ
PNAS (2022) 119 pp. e2118656119-e2118656119 [ DOI: doi:10.1073/pnas.2118656119 Pubmed: 35349344 ]
- Magnesium ion (24 Da, Ligand)
- Phospholipid-transporting atpase ic (148 kDa, Protein from Homo sapiens)
- Cell cycle control protein 50b (40 kDa, Protein from Homo sapiens)
- Atp8b1-cdc50b complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50A in the auto-inhibited E2P state
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 7vgi
Q-score: 0.528
Cheng MT, Chen Y, Chen ZP, Liu X, Zhang Z, Chen Y, Hou WT, Zhou CZ
PNAS (2022) 119 pp. e2118656119-e2118656119 [ DOI: doi:10.1073/pnas.2118656119 Pubmed: 35349344 ]
- Magnesium ion (24 Da, Ligand)
- Phospholipid-transporting atpase ic (148 kDa, Protein from Homo sapiens)
- Cell cycle control protein 50a (41 kDa, Protein from Homo sapiens)
- Atp8b1-cdc50a complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50A in the auto-inhibited E2Pi-PS state
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 7vgj
Q-score: 0.402
Cheng MT, Chen Y, Chen ZP, Liu X, Zhang Z, Chen Y, Hou WT, Zhou CZ
PNAS (2022) 119 pp. e2118656119-e2118656119 [ DOI: doi:10.1073/pnas.2118656119 Pubmed: 35349344 ]
- Phospholipid-transporting atpase ic (148 kDa, Protein from Homo sapiens)
- Atp8b1-cdc50a complex (Complex from Homo sapiens)
- Cell cycle control protein 50a (41 kDa, Protein from Homo sapiens)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)