Cryo-EM structure of SIDT1 in complex with phosphatidic acid
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8jul
Q-score: 0.55
Sun CR, Xu D, Yang F, Hou Z, Luo Y, Zhang CY, Shan G, Huang G, Yao X, Chen Y, Li Q, Zhou CZ
Cell Res (2024) 34 pp. 84-87 [ DOI: doi:10.1038/s41422-023-00889-x Pubmed: 37932444 ]
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Sid1 transmembrane family member 1 (93 kDa, Protein from Homo sapiens)
- Cryo-em structure of sidt1 in complex with phosphatidic acid (Complex from Homo sapiens)
Cryo-EM structure of SIDT1 E555Q mutant
Resolution: 2.38 Å
EM Method: Single-particle
Fitted PDBs: 8jun
Q-score: 0.574
Sun CR, Xu D, Yang F, Hou Z, Luo Y, Zhang CY, Shan G, Huang G, Yao X, Chen Y, Li Q, Zhou CZ
Cell Res (2024) 34 pp. 84-87 [ DOI: doi:10.1038/s41422-023-00889-x Pubmed: 37932444 ]
- Cryo-em structure of sidt1 e555q mutant (Complex from Homo sapiens)
- Sid1 transmembrane family member 1 (93 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs
Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7fdv
Q-score: 0.528
Xu D, Li Y, Yang F, Sun CR, Pan J, Wang L, Chen ZP, Fang SC, Yao X, Hou WT, Zhou CZ, Chen Y
Cell Rep (2022) 38 pp. 110298-110298 [ DOI: doi:10.1016/j.celrep.2022.110298 Pubmed: 35081353 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- The complex of human abcg1 with cholesterol and atp (152 kDa, Complex from Homo sapiens)
- Atp-binding cassette sub-family g member 1 (75 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- [(e,2s,3r)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate (703 Da, Ligand)
Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50B in the auto-inhibited E2P state
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 7vgh
Q-score: 0.522
Cheng MT, Chen Y, Chen ZP, Liu X, Zhang Z, Chen Y, Hou WT, Zhou CZ
PNAS (2022) 119 pp. e2118656119-e2118656119 [ DOI: doi:10.1073/pnas.2118656119 Pubmed: 35349344 ]
- Magnesium ion (24 Da, Ligand)
- Phospholipid-transporting atpase ic (148 kDa, Protein from Homo sapiens)
- Cell cycle control protein 50b (40 kDa, Protein from Homo sapiens)
- Atp8b1-cdc50b complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50A in the auto-inhibited E2P state
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 7vgi
Q-score: 0.528
Cheng MT, Chen Y, Chen ZP, Liu X, Zhang Z, Chen Y, Hou WT, Zhou CZ
PNAS (2022) 119 pp. e2118656119-e2118656119 [ DOI: doi:10.1073/pnas.2118656119 Pubmed: 35349344 ]
- Magnesium ion (24 Da, Ligand)
- Phospholipid-transporting atpase ic (148 kDa, Protein from Homo sapiens)
- Cell cycle control protein 50a (41 kDa, Protein from Homo sapiens)
- Atp8b1-cdc50a complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50A in the auto-inhibited E2Pi-PS state
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 7vgj
Q-score: 0.402
Cheng MT, Chen Y, Chen ZP, Liu X, Zhang Z, Chen Y, Hou WT, Zhou CZ
PNAS (2022) 119 pp. e2118656119-e2118656119 [ DOI: doi:10.1073/pnas.2118656119 Pubmed: 35349344 ]
- Phospholipid-transporting atpase ic (148 kDa, Protein from Homo sapiens)
- Atp8b1-cdc50a complex (Complex from Homo sapiens)
- Cell cycle control protein 50a (41 kDa, Protein from Homo sapiens)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)