Cryo-EM structure of the R399-bound GPBAR-Gs complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7xtq
Q-score: 0.456
Ma L, Yang F, Wu X, Mao C, Guo L, Miao T, Zang SK, Jiang X, Shen DD, Wei T, Zhou H, Wei Q, Li S, Shu Q, Feng S, Jiang C, Chu B, Du L, Sun JP, Yu X, Zhang Y, Zhang P
PNAS (2022) 119 pp. e2117054119-e2117054119 [ DOI: doi:10.1073/pnas.2117054119 Pubmed: 35858343 ]
- R399-bound gpbar-gs complex (Complex)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Gpbar (Complex from Homo sapiens)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Gs (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- [2-(2,5-dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2h-quinolin-1-yl)-methanone (399 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Nanobody-35 (Complex from synthetic construct)
- G-protein coupled bile acid receptor 1 (35 kDa, Protein from Homo sapiens)
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
Resolution: 0.65 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj1
Q-score: 0.973
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ Pubmed: 31334636 DOI: doi:10.1021/acs.analchem.9b01162 ]
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)
- Fus lc rac1 (Complex)
200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A
Resolution: 0.67 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj2
Q-score: 0.972
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ Pubmed: 31334636 DOI: doi:10.1021/acs.analchem.9b01162 ]
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)
- Fus lc rac1 (Complex)
120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A
Resolution: 0.6 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj3
Q-score: 0.962
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ Pubmed: 31334636 DOI: doi:10.1021/acs.analchem.9b01162 ]
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)
- Fus lc rac1 (Complex)
120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A
Resolution: 0.65 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj4
Q-score: 0.963
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ Pubmed: 31334636 DOI: doi:10.1021/acs.analchem.9b01162 ]
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)
- Fus lc rac1 (Complex)