Cryo-EM structure of the R399-bound GPBAR-Gs complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7xtq
Q-score: 0.456
Ma L, Yang F, Wu X, Mao C, Guo L, Miao T, Zang SK, Jiang X, Shen DD, Wei T, Zhou H, Wei Q, Li S, Shu Q, Feng S, Jiang C, Chu B, Du L, Sun JP, Yu X, Zhang Y, Zhang P
PNAS (2022) 119 pp. e2117054119-e2117054119 [ DOI: doi:10.1073/pnas.2117054119 Pubmed: 35858343 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- R399-bound gpbar-gs complex (Complex)
- [2-(2,5-dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2h-quinolin-1-yl)-methanone (399 Da, Ligand)
- Nanobody-35 (Complex from synthetic construct)
- G-protein coupled bile acid receptor 1 (35 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Gpbar (Complex from Homo sapiens)
- Gs (Complex from Homo sapiens)
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
Resolution: 0.65 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj1
Q-score: 0.973
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ DOI: doi:10.1021/acs.analchem.9b01162 Pubmed: 31334636 ]
- Fus lc rac1 (Complex)
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)
200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A
Resolution: 0.67 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj2
Q-score: 0.972
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ DOI: doi:10.1021/acs.analchem.9b01162 Pubmed: 31334636 ]
- Fus lc rac1 (Complex)
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)
120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A
Resolution: 0.6 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj3
Q-score: 0.962
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ DOI: doi:10.1021/acs.analchem.9b01162 Pubmed: 31334636 ]
- Fus lc rac1 (Complex)
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)
120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A
Resolution: 0.65 Å
EM Method: Electron Crystallography
Fitted PDBs: 6kj4
Q-score: 0.963
Zhou H, Luo F, Luo Z, Li D, Liu C, Li X
Anal Chem (2019) 91 pp. 10996-11003 [ DOI: doi:10.1021/acs.analchem.9b01162 Pubmed: 31334636 ]
- Fus lc rac1 (Complex)
- Water (18 Da, Ligand)
- Rna-binding protein fus (662 Da, Protein from Homo sapiens)