Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xog
Q-score: 0.294
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ Pubmed: 37993332 DOI: doi:10.1016/j.scib.2023.11.024 ]
- Spike glycoprotein,peptide (142 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Severe acute respiratory syndrome coronavirus (Complex from Severe acute respiratory syndrome coronavirus)
- Alpha-d-mannopyranose (180 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7xoe
Q-score: 0.301
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ Pubmed: 37993332 DOI: doi:10.1016/j.scib.2023.11.024 ]
Cryo-EM structure of the R399-bound GPBAR-Gs complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7xtq
Q-score: 0.456
Ma L, Yang F, Wu X, Mao C, Guo L, Miao T, Zang SK, Jiang X, Shen DD, Wei T, Zhou H, Wei Q, Li S, Shu Q, Feng S, Jiang C, Chu B, Du L, Sun JP, Yu X, Zhang Y, Zhang P
PNAS (2022) 119 pp. e2117054119-e2117054119 [ DOI: doi:10.1073/pnas.2117054119 Pubmed: 35858343 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Nanobody-35 (13 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- R399-bound gpbar-gs complex (Complex)
- [2-(2,5-dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2h-quinolin-1-yl)-methanone (399 Da, Ligand)
- Nanobody-35 (Complex from synthetic construct)
- G-protein coupled bile acid receptor 1 (35 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Gpbar (Complex from Homo sapiens)
- Gs (Complex from Homo sapiens)
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 6k7x
Q-score: 0.534
Zhuo W, Zhou H, Guo R, Yi J, Zhang L, Yu L, Sui Y, Zeng W, Wang P, Yang M
Protein Cell (2021) 12 pp. 220-229 [ Pubmed: 32862359 DOI: doi:10.1007/s13238-020-00776-w ]
- Cardiolipin (1 kDa, Ligand)
- Calcium uniporter protein, mitochondrial (32 kDa, Protein from Homo sapiens)
- Human mcu-emre complex (Complex from Homo sapiens)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Essential mcu regulator, mitochondrial (5 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6k7y
Q-score: 0.511
Zhuo W, Zhou H, Guo R, Yi J, Zhang L, Yu L, Sui Y, Zeng W, Wang P, Yang M
Protein Cell (2021) 12 pp. 220-229 [ Pubmed: 32862359 DOI: doi:10.1007/s13238-020-00776-w ]
- Cardiolipin (1 kDa, Ligand)
- Calcium uptake protein 1, mitochondrial (54 kDa, Protein from Homo sapiens)
- Intact human mitochondrial calcium uniporter complex with micu1/micu2 subunits (Complex from Homo sapiens)
- Calcium uniporter protein, mitochondrial (32 kDa, Protein from Homo sapiens)
- Calcium uptake protein 2, mitochondrial (39 kDa, Protein from Homo sapiens)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Essential mcu regulator, mitochondrial (5 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
A complex structure of arrestin-2 bound to neurotensin receptor 1
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 6pwc
Q-score: 0.23
Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, Cong Y, Edward Zhou X, Yu X, Eric Xu H
Cell Res (2019) 29 pp. 971-983 [ DOI: doi:10.1038/s41422-019-0256-2 Pubmed: 31776446 ]
- Beta-arrestin-1 (44 kDa, Protein from Homo sapiens)
- Fusion complex of bril-ntsr1-beta-arrestin1-fab30 (Complex from Homo sapiens)
- Fab30 light chain (23 kDa, Protein from synthetic construct)
- Neurotensin peptide (819 Da, Protein from synthetic construct)
- Neurotensin receptor type 1 (41 kDa, Protein from Homo sapiens)
- Fab30 heavy chain (25 kDa, Protein from synthetic construct)