Curved structure of mPIEZO1-S2472E
Resolution: 4.07 Å
EM Method: Single-particle
Fitted PDBs: 8ixn
Q-score: 0.301
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2024) [ DOI: doi:10.1016/j.neuron.2024.11.020 Pubmed: 39719701 ]
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- S2472e-curved structure (Complex from Mus musculus)
Flattened structure of mPIEZO1-S2472E
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8ixo
Q-score: 0.445
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2024) [ DOI: doi:10.1016/j.neuron.2024.11.020 Pubmed: 39719701 ]
- S2472e-intermediate structure (Complex from Mus musculus)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xog
Q-score: 0.294
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ DOI: doi:10.1016/j.scib.2023.11.024 Pubmed: 37993332 ]
- Severe acute respiratory syndrome coronavirus (Complex from Severe acute respiratory syndrome coronavirus)
- Spike glycoprotein,peptide (142 kDa, Protein from synthetic construct)
- Alpha-d-mannopyranose (180 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7xoe
Q-score: 0.301
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ DOI: doi:10.1016/j.scib.2023.11.024 Pubmed: 37993332 ]
MERS-CoV spike complex with S41 neutralizing antibody Fab Class4 (2u1d RBD with 3Fab)
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 7x25
Q-score: 0.129
Zhang S, Jia W, Zeng J, Li M, Wang Z, Zhou H, Zhang L, Wang X
Front Microbiol (2022) 13 pp. 988298-988298 [ DOI: doi:10.3389/fmicb.2022.988298 Pubmed: 36246239 ]
- Antibody s41 light chain (23 kDa, Protein from Homo sapiens)
- Antibody s41 heavy chain (23 kDa, Protein from Homo sapiens)
- Mers-cov spike with s41 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Mers-cov spike (Complex)
- S41 neutralizing antibody fab (Complex from Homo sapiens)
- Spike glycoprotein (148 kDa, Protein from Middle East respiratory syndrome-related coronavirus)
MERS-CoV spike complex with S41 neutralizing antibody Fab Class3 (2u1d RBD with 2Fab)
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 7x28
Q-score: 0.184
Zhang S, Jia W, Zeng J, Li M, Wang Z, Zhou H, Zhang L, Wang X
Front Microbiol (2022) 13 pp. 988298-988298 [ DOI: doi:10.3389/fmicb.2022.988298 Pubmed: 36246239 ]
- Antibody s41 light chain (23 kDa, Protein from Homo sapiens)
- Antibody s41 heavy chain (23 kDa, Protein from Homo sapiens)
- Mers-cov spike with s41 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Mers-cov spike (Complex)
- S41 neutralizing antibody fab (Complex from Homo sapiens)
- Spike glycoprotein (148 kDa, Protein from Middle East respiratory syndrome-related coronavirus)
S41 neutralizing antibody Fab(MERS-CoV)
Resolution: 3.685 Å
EM Method: Single-particle
Fitted PDBs: 7x26
Q-score: 0.427
Zhang S, Jia W, Zeng J, Li M, Wang Z, Zhou H, Zhang L, Wang X
Front Microbiol (2022) 13 pp. 988298-988298 [ DOI: doi:10.3389/fmicb.2022.988298 Pubmed: 36246239 ]
- Mers-cov spike rbd domain (Complex from Homo sapiens)
- Antibody s41 light chain (23 kDa, Protein from Homo sapiens)
- Antibody s41 heavy chain (23 kDa, Protein from Homo sapiens)
- S41 fab (Complex)
- Spike glycoprotein (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Mers-cov spike rbd domain with s41 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
MERS-CoV spike complex with S41 neutralizing antibody Fab Class2 (1u2d RBD with 2Fab)
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 7x29
Q-score: 0.447
Zhang S, Jia W, Zeng J, Li M, Wang Z, Zhou H, Zhang L, Wang X
Front Microbiol (2022) 13 pp. 988298-988298 [ DOI: doi:10.3389/fmicb.2022.988298 Pubmed: 36246239 ]
- Antibody s41 light chain (23 kDa, Protein from Homo sapiens)
- Antibody s41 heavy chain (23 kDa, Protein from Homo sapiens)
- Mers-cov spike with s41 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Mers-cov spike (Complex)
- S41 neutralizing antibody fab (Complex from Homo sapiens)
- Spike glycoprotein (148 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)