Curved structure of mPIEZO1-S2472E
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2025) 113 pp. 590- [ Pubmed: 39719701 DOI: doi:10.1016/j.neuron.2024.11.020 ]
- S2472e-curved structure (Complex from Mus musculus)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
Flattened structure of mPIEZO1-S2472E
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2025) 113 pp. 590- [ Pubmed: 39719701 DOI: doi:10.1016/j.neuron.2024.11.020 ]
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- S2472e-intermediate structure (Complex from Mus musculus)
Cryo-EM structure of the mouse Piezo1 isoform Piezo1.1
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6lqi
Q-score: 0.326
Geng J, Liu W, Zhou H, Zhang T, Wang L, Zhang M, Li Y, Shen B, Li X, Xiao B
Neuron (2020) 106 pp. 438- [ Pubmed: 32142647 DOI: doi:10.1016/j.neuron.2020.02.010 ]
- Piezo-type mechanosensitive ion channel component 1 (289 kDa, Protein from Mus musculus)
- Homo-trimer of piezo1.1 (880 kDa, Complex from Mus musculus)
A complex structure of arrestin-2 bound to neurotensin receptor 1
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 6pwc
Q-score: 0.23
Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, Cong Y, Edward Zhou X, Yu X, Eric Xu H
Cell Res (2019) 29 pp. 971-983 [ DOI: doi:10.1038/s41422-019-0256-2 Pubmed: 31776446 ]
- Beta-arrestin-1 (44 kDa, Protein from Homo sapiens)
- Fusion complex of bril-ntsr1-beta-arrestin1-fab30 (Complex from Homo sapiens)
- Fab30 light chain (23 kDa, Protein from synthetic construct)
- Neurotensin peptide (819 Da, Protein from synthetic construct)
- Neurotensin receptor type 1 (41 kDa, Protein from Homo sapiens)
- Fab30 heavy chain (25 kDa, Protein from synthetic construct)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5wrg
Q-score: 0.292
Gui M, Song W, Zhou H, Xu J, Chen S, Xiang Y, Wang X
Cell Res (2017) 27 pp. 119-129 [ DOI: doi:10.1038/cr.2016.152 Pubmed: 28008928 ]
- Sars-cov spike glycoprotein (400 kDa, Complex from SARS coronavirus)