Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
Resolution: 3.39 Å
EM Method: Single-particle
Fitted PDBs: 8wqa
Q-score: 0.362
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C
Nat Commun (2024) 15 pp. 3558-3558 [ DOI: doi:10.1038/s41467-024-47890-5 Pubmed: 38670995 ]
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of ccdc89 (conformation 1) (Complex from Homo sapiens)
- Coiled-coil domain-containing protein 89 (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wqb
Q-score: 0.39
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C
Nat Commun (2024) 15 pp. 3558-3558 [ DOI: doi:10.1038/s41467-024-47890-5 Pubmed: 38670995 ]
- Coiled-coil domain-containing protein 89 (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of ccdc89 (conformation 2) (Complex from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8wqc
Q-score: 0.352
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C
Nat Commun (2024) 15 pp. 3558-3558 [ DOI: doi:10.1038/s41467-024-47890-5 Pubmed: 38670995 ]
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Cryo-em structure of neddylated cul2-rbx1-elob-eloc-fem1b bound with the c-degron of cdk5r1 (Complex from Homo sapiens)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Nedd8 (8 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1)
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8wqe
Q-score: 0.372
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C
Nat Commun (2024) 15 pp. 3558-3558 [ DOI: doi:10.1038/s41467-024-47890-5 Pubmed: 38670995 ]
- Protein casp (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of cux1 (conformation 1) (Complex from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2)
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 8wqf
Q-score: 0.439
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C
Nat Commun (2024) 15 pp. 3558-3558 [ DOI: doi:10.1038/s41467-024-47890-5 Pubmed: 38670995 ]
- Protein casp (3 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Cryo-em structure of cul2-rbx1-elob-eloc-fem1b bound with the c-degron of cux1 (conformation 2) (Complex from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
Resolution: 4.09 Å
EM Method: Single-particle
Fitted PDBs: 8wqg
Q-score: 0.265
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C
Nat Commun (2024) 15 pp. 3558-3558 [ DOI: doi:10.1038/s41467-024-47890-5 Pubmed: 38670995 ]
- Cryo-em structure of neddylated cul2-rbx1-elob-eloc-fem1b bound with the c-degron of ccdc89 (conformation 1) (Complex from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Nedd8 (8 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 8wqh
Q-score: 0.362
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C
Nat Commun (2024) 15 pp. 3558-3558 [ DOI: doi:10.1038/s41467-024-47890-5 Pubmed: 38670995 ]
- Coiled-coil domain-containing protein 89 (3 kDa, Protein from Homo sapiens)
- Cryo-em structure of neddylated cul2-rbx1-elob-eloc-fem1b bound with the c-degron of ccdc89 (conformation 2) (Complex from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (11 kDa, Protein from Homo sapiens)
- Cullin-2 (87 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Elongin-c (10 kDa, Protein from Homo sapiens)
- Elongin-b (13 kDa, Protein from Homo sapiens)
- Protein fem-1 homolog b (70 kDa, Protein from Homo sapiens)
Structure of Enterobacter cloacae Cap2-CdnD02 2:2 complex
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7to3
Q-score: 0.528
Ledvina HE, Ye Q, Gu Y, Sullivan AE, Quan Y, Lau RK, Zhou H, Corbett KD, Whiteley AT
Nature (2023) 616 pp. 319-325 [ Pubmed: 36755092 DOI: doi:10.1038/s41586-022-05647-4 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cyclic amp-amp-gmp synthase (45 kDa, Protein from Enterobacter cloacae)
- Cap2 (67 kDa, Protein from Enterobacter cloacae)
- Quaternary complex of cap2 and cdnd02 in a 2:2 stoichiometry, with cdnd02 substrate captured at the active site of cap2. (224 kDa, Complex from Enterobacter cloacae)
Structure of Enterobacter cloacae Cap2-CdnD02 2:1 complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7tqd
Q-score: 0.517
Ledvina HE, Ye Q, Gu Y, Sullivan AE, Quan Y, Lau RK, Zhou H, Corbett KD, Whiteley AT
Nature (2023) 616 pp. 319-325 [ Pubmed: 36755092 DOI: doi:10.1038/s41586-022-05647-4 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cyclic amp-amp-gmp synthase (45 kDa, Protein from Enterobacter cloacae)
- Ternary complex of cap2 and cdnd02 in a 2:1 stoichiometry. (179 kDa, Complex from Enterobacter cloacae)
- Cap2 (67 kDa, Protein from Enterobacter cloacae)
Structure of Leishmania tarentolae IFT-A (state 1)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8f5o
Q-score: 0.335
Meleppattu S, Zhou H, Dai J, Gui M, Brown A
Cell (2022) 185 pp. 4986- [ Pubmed: 36563665 DOI: doi:10.1016/j.cell.2022.11.033 ]
- Tpr_region domain-containing protein (180 kDa, Protein from Leishmania tarentolae)
- Wd_repeats_region domain-containing protein (182 kDa, Protein from Leishmania tarentolae)
- Net domain-containing protein (38 kDa, Protein from Leishmania tarentolae)
- Intraflagellar transport protein 122b, putative (139 kDa, Protein from Leishmania tarentolae)
- Ift-a (Complex from Leishmania tarentolae)
- Wd_repeats_region domain-containing protein (152 kDa, Protein from Leishmania tarentolae)
- Zinc ion (65 Da, Ligand)
- Intraflagellar transport protein 122 homolog (144 kDa, Protein from Leishmania tarentolae)