Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 monomer state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8vh4
Q-score: 0.333
Li X, Zhu H, Huang BT, Li X, Kim H, Tan H, Zhang Y, Choi I, Peng J, Xu P, Sun J, Yue Z
Nat Commun (2024) 15 pp. 8434-8434 [ Pubmed: 39343966 DOI: doi:10.1038/s41467-024-52723-6 ]
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Rab12-lrrk2 (Complex from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Ras-related protein rab-12 (20 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 dimer state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8vh5
Q-score: 0.248
Li X, Zhu H, Huang BT, Li X, Kim H, Tan H, Zhang Y, Choi I, Peng J, Xu P, Sun J, Yue Z
Nat Commun (2024) 15 pp. 8434-8434 [ Pubmed: 39343966 DOI: doi:10.1038/s41467-024-52723-6 ]
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Rab12-lrrk2 (Complex from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Ras-related protein rab-12 (20 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cryo-EM structure of Cas8-HNH system at full R-loop state
Resolution: 2.51 Å
EM Method: Single-particle
Fitted PDBs: 8z0k
Q-score: 0.551
Li X, Liu Y, Han J, Zhang L, Liu Z, Wang L, Zhang S, Zhang Q, Fu P, Yin H, Zhu H, Zhang H
EMBO J (2024) 43 pp. 4656-4667 [ Pubmed: 39251884 DOI: doi:10.1038/s44318-024-00229-8 ]
- Type i-f crispr-associated endoribonuclease cas6/csy4 (20 kDa, Protein from Selenomonas sp.)
- Dna (37-mer) (11 kDa, DNA from Selenomonas sp.)
- Dna (5'-d(p*gp*tp*gp*cp*gp*gp*a)-3') (2 kDa, DNA from Selenomonas sp.)
- Cryo-em structure of cas8-hnh system at full r-loop state (Complex from Selenomonas sp.)
- Hnh endonuclease (39 kDa, Protein from Selenomonas sp.)
- Rna (69-mer) (22 kDa, RNA from Selenomonas sp.)
- Type i-f crispr-associated protein csy3 (37 kDa, Protein from Selenomonas sp.)
- Hypothetical protein j6n51_11000 (28 kDa, Protein from Selenomonas sp.)
Cryo-EM structure of Cas8-HNH system at partial R-loop state
Resolution: 2.57 Å
EM Method: Single-particle
Fitted PDBs: 8z0l
Q-score: 0.549
Li X, Liu Y, Han J, Zhang L, Liu Z, Wang L, Zhang S, Zhang Q, Fu P, Yin H, Zhu H, Zhang H
EMBO J (2024) 43 pp. 4656-4667 [ Pubmed: 39251884 DOI: doi:10.1038/s44318-024-00229-8 ]
- Type i-f crispr-associated endoribonuclease cas6/csy4 (20 kDa, Protein from Selenomonas sp.)
- Dna (5'-d(p*gp*tp*gp*cp*gp*gp*a)-3') (2 kDa, DNA from Selenomonas sp.)
- Dna (32-mer) (9 kDa, DNA from Selenomonas sp.)
- Cryo-em structure of cas8-hnh system at partial r-loop state (Complex from Selenomonas sp.)
- Hnh endonuclease (39 kDa, Protein from Selenomonas sp.)
- Rna (69-mer) (22 kDa, RNA from Selenomonas sp.)
- Type i-f crispr-associated protein csy3 (37 kDa, Protein from Selenomonas sp.)
- Hypothetical protein j6n51_11000 (28 kDa, Protein from Selenomonas sp.)
Cryo-EM structure of Cas8-HNH system at target free state
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8zdy
Q-score: 0.42
Li X, Liu Y, Han J, Zhang L, Liu Z, Wang L, Zhang S, Zhang Q, Fu P, Yin H, Zhu H, Zhang H
EMBO J (2024) 43 pp. 4656-4667 [ Pubmed: 39251884 DOI: doi:10.1038/s44318-024-00229-8 ]
- A protein (28 kDa, Protein from Selenomonas sp.)
- A protein (20 kDa, Protein from Selenomonas sp.)
- A protein (38 kDa, Protein from Selenomonas sp.)
- A protein (39 kDa, Protein from Selenomonas sp.)
- A protein (Complex from Selenomonas sp.)
- Rna (58-mer) (22 kDa, RNA from Selenomonas sp.)
Cryo-EM structure of Cas8-HNH system at ssDNA-bound state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8znr
Q-score: 0.505
Li X, Liu Y, Han J, Zhang L, Liu Z, Wang L, Zhang S, Zhang Q, Fu P, Yin H, Zhu H, Zhang H
EMBO J (2024) 43 pp. 4656-4667 [ Pubmed: 39251884 DOI: doi:10.1038/s44318-024-00229-8 ]
- Protein structure (20 kDa, Protein from Selenomonas sp.)
- Rna (56-mer) (22 kDa, RNA from Selenomonas sp.)
- Protein structure (39 kDa, Protein from Selenomonas sp.)
- Protein structure (37 kDa, Protein from Selenomonas sp.)
- Protein structure (28 kDa, Protein from Selenomonas sp.)
- Protein complex (Complex from Selenomonas sp.)
- Dna (35-mer) (10 kDa, DNA from Selenomonas sp.)
SARS-CoV-2 Omicron BA.1 spike protein in complex with a self-assembling trivalent nanobody Tr67
Qin Q, Jiang X, Huo L, Qian J, Yu H, Zhu H, Du W, Cao Y, Zhang X, Huang Q
J Nanobiotechnology (2024) 22 pp. 58-58 [ DOI: doi:10.1186/s12951-024-02329-3 Pubmed: 38341574 ]
- Trivalent nanobody (Complex from synthetic construct)
- Sars-cov-2 omicron ba.1 spike protein in complex with a self-assembling trivalent nanobody tr67 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.1 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
Structure of the wild-type Arabidopsis ABCB19 in the apo state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8woi
Q-score: 0.49
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8wom
Q-score: 0.451
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide and AMP-PNP bound state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8woo
Q-score: 0.401
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
- Abc transporter b family member 19 (136 kDa, Protein from Arabidopsis thaliana)
- Purified wild-type abcb19 protein in complex with brassinolide and amp-pnp (Cellular component from Arabidopsis thaliana)
- Magnesium ion (24 Da, Ligand)
- Brassinolide (480 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)