Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8fdw
Q-score: 0.327
Shi W, Cai Y, Zhu H, Peng H, Voyer J, Rits-Volloch S, Cao H, Mayer ML, Song K, Xu C, Lu J, Zhang J, Chen B
Nature (2023) 619 pp. 403-409 [ Pubmed: 37285872 DOI: doi:10.1038/s41586-023-06273-4 ]
- Spike protein s2 (68 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sras-cov-2 postfusion spike protein in nanodisc (210 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Alpha-d-mannopyranose (180 Da, Ligand)
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7wp8
Q-score: 0.441
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk1628x in complex with three neutralizing antibodies (Complex from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2b4 light chain (12 kDa, Protein from Mus musculus)
- Spike protein stfk1628x (Complex)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2b4 heavy chain (13 kDa, Protein from Mus musculus)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 7wp6
Q-score: 0.438
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- 36h6 light chain (12 kDa, Protein from Mus musculus)
- Spike protein stfk (Complex)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 36h6 heavy chain (13 kDa, Protein from Mus musculus)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk in complex with three neutralizing antibodies (Complex from Mus musculus)
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ef9
Q-score: 0.605
Li C, Zhu H, Jin S, Maksoud LM, Jain N, Sun J, Gao Y
Nucleic Acids Res (2023) 51 pp. 463-474 [ Pubmed: 36583344 DOI: doi:10.1093/nar/gkac1201 ]
- Magnesium ion (24 Da, Ligand)
- Ternary complex of lates calcarifer dna polymerase theta with duplex dna and incoming nucleotide (Complex from Lates calcarifer)
- Dna (5'-d(*ap*gp*cp*tp*cp*tp*ap*cp*gp*gp*ap*tp*gp*c)-3') (8 kDa, DNA from Lates calcarifer)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Dna (5'-d(*ap*gp*cp*ap*tp*cp*cp*gp*tp*ap*gp*(2da))-3') (5 kDa, DNA from Lates calcarifer)
- Dna polymerase theta (95 kDa, Protein from Lates calcarifer)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8efc
Q-score: 0.492
Li C, Zhu H, Jin S, Maksoud LM, Jain N, Sun J, Gao Y
Nucleic Acids Res (2023) 51 pp. 463-474 [ Pubmed: 36583344 DOI: doi:10.1093/nar/gkac1201 ]
- Magnesium ion (24 Da, Ligand)
- Dna (5'-d(*ap*gp*cp*tp*cp*tp*ap*cp*gp*gp*ap*tp*gp*cp*cp*tp*cp*ap*cp*ap*g)-3') (8 kDa, DNA from Lates calcarifer)
- Ternary complex of lates calcarifer dna polymerase theta with duplex dna and incoming nucleotide (Complex from Lates calcarifer)
- 2'-deoxyguanosine-5'-triphosphate (507 Da, Ligand)
- Dna (5'-d(*ap*cp*tp*gp*tp*gp*ap*gp*gp*cp*ap*tp*cp*cp*gp*tp*ap*gp*(2da))-3') (6 kDa, DNA from Lates calcarifer)
- Dna polymerase theta (95 kDa, Protein from Lates calcarifer)
Structure of Lates calcarifer DNA polymerase theta polymerase domain with hairpin DNA
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8efk
Q-score: 0.525
Li C, Zhu H, Jin S, Maksoud LM, Jain N, Sun J, Gao Y
Nucleic Acids Res (2023) 51 pp. 463-474 [ Pubmed: 36583344 DOI: doi:10.1093/nar/gkac1201 ]
- Lates calcarifer dna polymerase theta (95 kDa, Protein from Lates calcarifer)
- Magnesium ion (24 Da, Ligand)
- Ternary complex of lates calcarifer dna polymerase theta with duplex dna and incoming nucleotide (Complex from Lates calcarifer)
- 2',3'-dideoxyadenosine triphosphate (475 Da, Ligand)
- Dna (5'-d(p*tp*tp*tp*tp*gp*gp*cp*tp*tp*tp*tp*gp*cp*cp*(2da))-3') (7 kDa, DNA from Lates calcarifer)
Human AAA+ ATPase VCP mutant - T76A, ADP-bound form
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7bp8
Q-score: 0.411
Zhu K, Cai Y, Si X, Ye Z, Gao Y, Liu C, Wang R, Ma Z, Zhu H, Zhang L, Li S, Zhang H, Yue J
Cell Death Differ. (2022) [ Pubmed: 35430615 DOI: doi:10.1038/s41418-022-01000-4 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
- Transitional endoplasmic reticulum atpase, vcp. (97 MDa, Complex from Homo sapiens)
Human AAA+ ATPase VCP mutant - T76E, ADP-bound form
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7bp9
Q-score: 0.423
Zhu K, Cai Y, Si X, Ye Z, Gao Y, Liu C, Wang R, Ma Z, Zhu H, Zhang L, Li S, Zhang H, Yue J
Cell Death Differ. (2022) [ Pubmed: 35430615 DOI: doi:10.1038/s41418-022-01000-4 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
- Transitional endoplasmic reticulum atpase, vcp. (97 MDa, Complex from Homo sapiens)