Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7lht
Q-score: 0.376
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Lrrk2 (Complex from Homo sapiens)
Structure of the LRRK2 monomer
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7lhw
Q-score: 0.406
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Lrrk2 (Complex from Homo sapiens)
Structure of the LRRK2 G2019S mutant
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7li3
Q-score: 0.402
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Lrrk2 g2019s mutant (Complex from Homo sapiens)
Structure of LRRK2 after symmetry expansion
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7li4
Q-score: 0.491
Myasnikov A, Zhu H, Hixson P, Xie B, Yu K, Pitre A, Peng J, Sun J
Cell (2021) 184 pp. 3519- [ Pubmed: 34107286 DOI: doi:10.1016/j.cell.2021.05.004 ]
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Lrrk2 (Complex from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6plp
Q-score: 0.422
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- Glycine receptor in complex with gaba (250 kDa, Complex from Danio rerio)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6plq
Q-score: 0.088
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Glycine receptor in complex with gaba (250 MDa, Complex from Danio rerio)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, super-open state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6plw
Q-score: 0.47
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Glycine receptor in complex with gaba (250 MDa, Complex from Danio rerio)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, super-open state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6pm0
Q-score: 0.479
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Glycine receptor in complex with taurine (250 MDa, Complex from Danio rerio)
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- 2-aminoethanesulfonic acid (125 Da, Ligand)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6pm1
Q-score: 0.535
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- Glycine receptor in complex with taurine (250 kDa, Complex from Danio rerio)
- 2-aminoethanesulfonic acid (125 Da, Ligand)
CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, open state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6pm2
Q-score: 0.504
Yu J, Zhu H, Lape R, Greiner T, Du J, Lu W, Sivilotti L, Gouaux E
Cell (2021) 184 pp. 957-968.e21 [ Pubmed: 33567265 DOI: doi:10.1016/j.cell.2021.01.026 ]
- Glycine receptor subunit alphaz1 (52 kDa, Protein from Danio rerio)
- Glycine receptor in complex with taurine (250 kDa, Complex from Danio rerio)
- 2-aminoethanesulfonic acid (125 Da, Ligand)