Small conductance mechanosensitive channel MscS
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7raz
Q-score: 0.418
Catalano C, Ben-Hail D, Qiu W, des Georges A, Guo Y
To Be Published
Low conductance mechanosensitive channel YnaI
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7n4t
Q-score: 0.557
Catalano C, Ben-Hail D, Qiu W, Blount P, des Georges A, Guo Y
Membranes (Basel) (2021) 11 [ DOI: doi:10.3390/membranes11110849 Pubmed: 34832078 ]
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6pv6
Q-score: 0.18
Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A
Nat Commun (2020) 11 pp. 4734-4734 [ DOI: doi:10.1038/s41467-020-18403-x Pubmed: 32948759 ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 1 bound to fkbp1b (2 MDa, Complex from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ryanodine receptor 1 (502 kDa, Protein from Oryctolagus cuniculus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7jmf
Q-score: 0.11
Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A
Nat Commun (2020) 11 pp. 4734-4734 [ DOI: doi:10.1038/s41467-020-18403-x Pubmed: 32948759 ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 1 bound to fkbp1b (2 MDa, Complex from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ryanodine receptor 1 (502 kDa, Protein from Oryctolagus cuniculus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7jmg
Q-score: 0.155
Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A
Nat Commun (2020) 11 pp. 4734-4734 [ DOI: doi:10.1038/s41467-020-18403-x Pubmed: 32948759 ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 1 bound to fkbp1b (2 MDa, Complex from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ryanodine receptor type 1 (502 kDa, Protein from Oryctolagus cuniculus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7jmh
Q-score: 0.132
Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A
Nat Commun (2020) 11 pp. 4734-4734 [ DOI: doi:10.1038/s41467-020-18403-x Pubmed: 32948759 ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 1 bound to fkbp1b (2 MDa, Complex from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ryanodine receptor type 1 (502 kDa, Protein from Oryctolagus cuniculus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7jmi
Q-score: 0.153
Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A
Nat Commun (2020) 11 pp. 4734-4734 [ DOI: doi:10.1038/s41467-020-18403-x Pubmed: 32948759 ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 1 bound to fkbp1b (2 MDa, Complex from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ryanodine receptor type 1 (502 kDa, Protein from Oryctolagus cuniculus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7jmj
Q-score: 0.133
Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A
Nat Commun (2020) 11 pp. 4734-4734 [ DOI: doi:10.1038/s41467-020-18403-x Pubmed: 32948759 ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 1 bound to fkbp1b (2 MDa, Complex from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ryanodine receptor type 1 (502 kDa, Protein from Oryctolagus cuniculus)
Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6ni2
Q-score: 0.348
Nguyen AH, Thomsen ARB, Cahill 3rd TJ, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Little 4th J, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ
Nat Struct Mol Biol (2019) 26 pp. 1123-1131 [ DOI: doi:10.1038/s41594-019-0330-y Pubmed: 31740855 ]
- Beta-arrestin-1 (44 kDa, Protein from Bos taurus)
- Fab30 light chain (23 kDa, Protein from synthetic construct)
- Fab30 heavy chain (25 kDa, Protein from synthetic construct)
- Vasopressin v2 receptor (3 kDa, Protein from Homo sapiens)
- Vasopressin 2 tail (Complex from Homo sapiens)
- Nanobody 32 (Complex from Lama glama)
- Nanobody 32 (13 kDa, Protein from Lama glama)
- Fab30 (Complex from synthetic construct)
- Beta-arrestin-1 (Complex from Bos taurus)
- Stabilized beta-arrestin 1-v2t subcomplex of a gpcr-g protein-beta-arrestin mega-complex (Complex)
B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6ni3
Q-score: 0.39
Nguyen AH, Thomsen ARB, Cahill 3rd TJ, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Little 4th J, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ
Nat Struct Mol Biol (2019) 26 pp. 1123-1131 [ DOI: doi:10.1038/s41594-019-0330-y Pubmed: 31740855 ]
- Nanobody 35 (Complex from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- B2v2r-gs protein subcomplex of a gpcr-g protein-beta-arrestin mega-complex (Complex)
- B2v2r-gs protein subcomplex (Complex from Homo sapiens)
- Endolysin,beta-2 adrenergic receptor chimera (57 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (44 kDa, Protein from Homo sapiens)
- 8-[(1r)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2h-1,4-benzoxazin-3(4h)-one (370 Da, Ligand)