Electron Microscopy Data Bank

Release date: Feb. 28, 2023
Dataset size: 33.7 GB
Experiment type: EMDB

Marcink T, Zipursky G, Cheng W, Stearns K, Stenglein S, Golub K, Cohen F, Bovier F, Pfalmer D, Greninger A, Porotto M, des Georges A, Moscona A

Sci Adv (2023) 9 [ Pubmed: 36763666 DOI: 10.1126/sciadv.ade2727 ]

Image sets:

Unaligned Tilt Series of HPIV3 clinical isolate virions

EMPIAR-11104

Release date: Feb. 28, 2023
Dataset size: 19.1 GB
Experiment type: EMDB

Marcink T, Zipursky G, Cheng W, Stearns K, Stenglein S, Golub K, Cohen F, Bovier F, Pfalmer D, Greninger A, Porotto M, des Georges A, Moscona A

Sci Adv (2023) 9 [ Pubmed: 36763666 DOI: 10.1126/sciadv.ade2727 ]

Image sets:

Unaligned Tilt Series of HPIV3 clinical isolate virions in the presence of an F neutralizing antibody

EMD-27550

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Subtomogram average of the HN/F fusion complex on authentic viral surfaces of HPIV3

Release date: Feb. 22, 2023
Resolution: 10.2 Å
EM Method: Subtomogram averaging

Marcink TC, Zipursky G, Cheng W, Stearns K, Stenglein S, Golub K, Cohen F, Bovier F, Pfalmer D, Greninger AL, Porotto M, des Georges A, Moscona A

Sci Adv (2023) 9 pp. eade2727-eade2727 [ Pubmed: 36763666 DOI: doi:10.1126/sciadv.ade2727 ]

Sample:

Human respirovirus 3 (Virus from Human respirovirus 3)

EMD-27551

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Subtomogram average of the PIA174 Fab/F complex on authentic viral surfaces of HPIV3

Release date: Feb. 22, 2023
Resolution: 16.5 Å
EM Method: Subtomogram averaging

Marcink TC, Zipursky G, Cheng W, Stearns K, Stenglein S, Golub K, Cohen F, Bovier F, Pfalmer D, Greninger AL, Porotto M, des Georges A, Moscona A

Sci Adv (2023) 9 pp. eade2727-eade2727 [ Pubmed: 36763666 DOI: doi:10.1126/sciadv.ade2727 ]

Sample:

Human respirovirus 3 (Virus from Human respirovirus 3)

EMPIAR-10788

Release date: Oct. 7, 2022
Dataset size: 9.6 GB
Experiment type: EMDB

Marcink TC, Kicmal T, Armbruster E, Zhang Z, Zipursky G, Golub KL, Idris M, Khao J, Drew-Bear J, McGill G, Gallagher T, Porotto M, des Georges A, Moscona A

Sci Adv (2022) 8 [ Pubmed: 35984891 DOI: 10.1126/sciadv.abo3153 ]

Image sets:

Prealigned tilt series of SARS-CoV-2 spike-bearing virus-like particles (VLPs) interacting with hACE2-bearing extracellular vesicles (tEVs)

EMD-24599

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Tomogram of SARS-CoV-2 spike-bearing virus-like particles (VLPs) interacting with hACE2-bearing extracellular vesicles (tEVs), showing various intermediate states of the SARS-CoV-2 spike protein (Fig. 2M,N, Fig 3J, and Supp. Movie 1 of the manuscript Marcink et al., 2021).

Release date: Aug. 31, 2022
EM Method: Tomography

Marcink TC, Kicmal T, Armbruster E, Zhang Z, Zipursky G, Golub KL, Idris M, Khao J, Drew-Bear J, McGill G, Gallagher T, Porotto M, des Georges A, Moscona A

Sci Adv (2022) 8 pp. eabo3153-eabo3153 [ DOI: doi:10.1126/sciadv.abo3153 Pubmed: 35984891 ]

Sample:

EMD-24600

Download Map Raw data

Tomogram of SARS-CoV-2 spike-bearing virus-like particles (VLPs) interacting with hACE2-bearing extracellular vesicles (tEVs), showing various intermediate states of the SARS-CoV-2 spike protein (Fig. 2K,L, and Supp. Movie 2 of the manuscript Marcink et. al 2021,).

Release date: Aug. 31, 2022
EM Method: Tomography

Marcink TC, Kicmal T, Armbruster E, Zhang Z, Zipursky G, Golub KL, Idris M, Khao J, Drew-Bear J, McGill G, Gallagher T, Porotto M, des Georges A, Moscona A

Sci Adv (2022) 8 pp. eabo3153-eabo3153 [ DOI: doi:10.1126/sciadv.abo3153 Pubmed: 35984891 ]

Sample:

EMD-24601

Download Map Raw data

Tomogram of SARS-CoV-2 spike-bearing virus-like particles (VLPs) interacting with hACE2-bearing extracellular vesicles (tEVs), showing various intermediate states of the SARS-CoV-2 spike protein (Fig. 4B-E and Supp. Movie 3 of manuscript Marcink et al., 2021).

Release date: Aug. 31, 2022
EM Method: Tomography

Marcink TC, Kicmal T, Armbruster E, Zhang Z, Zipursky G, Golub KL, Idris M, Khao J, Drew-Bear J, McGill G, Gallagher T, Porotto M, des Georges A, Moscona A

Sci Adv (2022) 8 pp. eabo3153-eabo3153 [ DOI: doi:10.1126/sciadv.abo3153 Pubmed: 35984891 ]

Sample:

EMD-24602

Download Map Raw data

Tomogram of SARS-CoV-2 spike-bearing virus-like particles (VLPs) interacting with hACE2-bearing extracellular vesicles (tEVs), showing various intermediate states of the SARS-CoV-2 spike protein (Fig 2E-G of the manuscript Marcink et al., 2021).

Release date: Aug. 31, 2022
EM Method: Tomography

Marcink TC, Kicmal T, Armbruster E, Zhang Z, Zipursky G, Golub KL, Idris M, Khao J, Drew-Bear J, McGill G, Gallagher T, Porotto M, des Georges A, Moscona A

Sci Adv (2022) 8 pp. eabo3153-eabo3153 [ DOI: doi:10.1126/sciadv.abo3153 Pubmed: 35984891 ]

Sample:

EMD-24603

Download Map Raw data

Tomogram of SARS-CoV-2 spike-bearing virus-like particles (VLPs) interacting with hACE2-bearing extracellular vesicles (tEVs), showing various intermediate states of the SARS-CoV-2 spike protein (Fig. 3D,E of the manuscript Marcink et al., 2021).

Release date: Aug. 31, 2022
EM Method: Tomography

Marcink TC, Kicmal T, Armbruster E, Zhang Z, Zipursky G, Golub KL, Idris M, Khao J, Drew-Bear J, McGill G, Gallagher T, Porotto M, des Georges A, Moscona A

Sci Adv (2022) 8 pp. eabo3153-eabo3153 [ DOI: doi:10.1126/sciadv.abo3153 Pubmed: 35984891 ]

Sample:

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