Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7kcr
Q-score: 0.436
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ
Viruses (2020) 12 [ DOI: doi:10.3390/v12121346 Pubmed: 33255202 ]
- Adi30056 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Monoclonal antibody adi30056 (Complex from Homo sapiens)
- Zika virus in complex with monoclonal antibody adi30056 (15 MDa, Complex)
- Envelope protein e (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Adi30056 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Membrane protein m (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ Pubmed: 30642974 DOI: doi:10.1073/pnas.1815432116 ]
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Structure of Zika virus at a resolution of 3.1 Angstrom
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6co8
Q-score: 0.507
Sevvana M, Long F, Miller AS, Klose T, Buda G, Sun L, Kuhn RJ, Rossmann MG
Structure (2018) 26 pp. 1169- [ DOI: doi:10.1016/j.str.2018.05.006 Pubmed: 29958768 ]
- E protein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- M protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 5uhy
Q-score: 0.148
Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE, Kuhn RJ, Rossmann MG
Nat Commun (2017) 8 pp. 14722-14722 [ DOI: doi:10.1038/ncomms14722 Pubmed: 28300075 ]
- Zv67 fab chain 1 (23 kDa, Protein from Homo sapiens)
- Zika virus with zikv117 fab (Complex from Zika virus)
- Envelope protein (43 kDa, Protein from Zika virus)
- Zv67 fab chain 2 (23 kDa, Protein from Homo sapiens)
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab CHK265
Resolution: 16.9 Å
EM Method: Single-particle
Fitted PDBs: 5any
Q-score: -0.013
Fox JM, Long F, Edeling MA, Lin H, Duijl-Richter M, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS
Cell (2015) 163 pp. 1095-1107 [ DOI: doi:10.1016/J.CELL.2015.10.050 Pubmed: 26553503 ]
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab 4J21
Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE, Diamond MS, Rossmann MG
PNAS (2015) 112 pp. 13898-13903 [ Pubmed: 26504196 DOI: doi:10.1073/pnas.1515558112 ]
Electron cryo-microscopy of chikungunya virus in complex with neutralizing antibody Fab 5M16
Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE, Diamond MS, Rossmann MG
PNAS (2015) 112 pp. 13898-13903 [ DOI: doi:10.1073/pnas.1515558112 Pubmed: 26504196 ]