Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7kcr
Q-score: 0.436
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ
Viruses (2020) 12 [ DOI: doi:10.3390/v12121346 Pubmed: 33255202 ]
- Adi30056 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Monoclonal antibody adi30056 (Complex from Homo sapiens)
- Zika virus in complex with monoclonal antibody adi30056 (15 MDa, Complex)
- Envelope protein e (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Adi30056 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Membrane protein m (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Native Mayaro virus cryo EM map, resolution 4.8 Angstroms
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 6w2u
Q-score: 0.439
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699- [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Mayaro virus (Complex from Mayaro virus)
- Spike glycoprotein e1 (41 kDa, Protein from Mayaro virus (strain Brazil))
- Native mayaro virus (Complex)
- Spike glycoprotein e2 (38 kDa, Protein from Mayaro virus (strain Brazil))
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w09
Q-score: 0.34
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Chikungunya virus-fab complex (Complex)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Chikungunya virus)
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- E3 (6 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Virus from Chikungunya virus)
- E1 glycoprotein (42 kDa, Protein from Chikungunya virus)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w1c
Q-score: 0.35
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Mayaro virus (Virus from Mayaro virus)
- Fab chk-265 (Complex from Homo sapiens)
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Mayaro virus-fab chk-265 complex (Complex)
- E1 glycoprotein (41 kDa, Protein from Mayaro virus (strain Brazil))
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Mayaro virus (strain Brazil))
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6wds
Q-score: 0.631
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Ev68-159 heavy chain (13 kDa, Protein from Homo sapiens)
- Human antibody ev68-159 (Complex from Homo sapiens)
- Enterovirus d68 in complex with human monoclonal antibody ev68-159 (Complex)
- Ev68-159 light chain (11 kDa, Protein from Homo sapiens)
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Enterovirus d68 (Virus from Enterovirus D68)
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wdt
Q-score: 0.589
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Human monoclonal antibody ev68-228 (Complex from Homo sapiens)
- Ev68-228 heavy chain (14 kDa, Protein from Homo sapiens)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Enterovirus d68 in complex with human monoclonal antibody ev68-228 (Complex)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Ev68-228 light chain (11 kDa, Protein from Homo sapiens)
- Enterovirus d68 (Virus from Enterovirus D68)
Eastern equine encephalitis virus (EEEV)
Chen CL, Hasan SS, Klose T, Sun Y, Buda G, Sun C, Klimstra WB, Rossmann MG
PNAS (2020) 117 pp. 8890-8899 [ DOI: doi:10.1073/pnas.1910670117 Pubmed: 32245806 ]
Rhinovirus C15 complexed with domain I of receptor CDHR3
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6ppo
Q-score: 0.581
Sun Y, Watters K, Hill MG, Fang Q, Liu Y, Kuhn RJ, Klose T, Rossmann MG, Palmenberg AC
PNAS (2020) 117 pp. 6784-6791 [ DOI: doi:10.1073/pnas.1921640117 Pubmed: 32152109 ]
- Capsid protein vp4 (7 kDa, Protein from Rhinovirus C)
- Capsid protein vp1 (31 kDa, Protein from Rhinovirus C)
- Rhinovirus c (Virus from Rhinovirus C)
- Cadherin-related family member 3 (14 kDa, Protein from Homo sapiens)
- Complex of rhinovirus c15 with domain i from human cdhr3 (6 MDa, Complex)
- Calcium ion (40 Da, Ligand)
- Capsid protein vp2 (29 kDa, Protein from Rhinovirus C)
- Domain i from human cdhr3 (Complex from Homo sapiens)
- Capsid protein vp3 (25 kDa, Protein from Rhinovirus C)
Rhinovirus C15 complexed with domains I and II of receptor CDHR3
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6psf
Q-score: 0.554
Sun Y, Watters K, Hill MG, Fang Q, Liu Y, Kuhn RJ, Klose T, Rossmann MG, Palmenberg AC
PNAS (2020) 117 pp. 6784-6791 [ Pubmed: 32152109 DOI: doi:10.1073/pnas.1921640117 ]
- Capsid protein vp3 (25 kDa, Protein from Rhinovirus C)
- Capsid protein vp2 (29 kDa, Protein from Rhinovirus C)
- Rhinovirus c (Virus from Rhinovirus C)
- Capsid protein vp4 (7 kDa, Protein from Rhinovirus C)
- Domain i and domain ii (ec1-2) from human cdhr3 (Complex from Homo sapiens)
- Complex of rhinovirus c15 with domain i and domain ii (ec1-2) from human cdhr3 (6 MDa, Complex)
- Cadherin-related family member 3 (26 kDa, Protein from Homo sapiens)
- Capsid protein vp1 (31 kDa, Protein from Rhinovirus C)
Epstein-Barr Virus glycoproteins, gH/gL/gp42 inserted ferritin nanoparticles
Bu W, Joyce MG, Nguyen H, Banh DV, Aguilar F, Tariq Z, Yap ML, Tsujimura Y, Gillespie RA, Tsybovsky Y, Andrews SF, Narpala SR, McDermott AB, Rossmann MG, Yasutomi Y, Nabel GJ, Kanekiyo M, Cohen JI
Immunity (2019) 50 pp. 1305-1316.e6 [ DOI: doi:10.1016/j.immuni.2019.03.010 Pubmed: 30979688 ]