Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7kcr
Q-score: 0.436
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ
Viruses (2020) 12 [ DOI: doi:10.3390/v12121346 Pubmed: 33255202 ]
- Adi30056 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Monoclonal antibody adi30056 (Complex from Homo sapiens)
- Zika virus in complex with monoclonal antibody adi30056 (15 MDa, Complex)
- Envelope protein e (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Adi30056 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Membrane protein m (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Resolution: 6.33 Å
EM Method: Single-particle
Fitted PDBs: 6vyv
Q-score: 0.339
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Ross river virus (strain t48) (Virus from Ross river virus (strain T48))
- E1 glycoprotein (42 kDa, Protein from Ross river virus (strain T48))
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Ross river virus (strain T48))
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w09
Q-score: 0.34
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Chikungunya virus-fab complex (Complex)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Chikungunya virus)
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- E3 (6 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Virus from Chikungunya virus)
- E1 glycoprotein (42 kDa, Protein from Chikungunya virus)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w1c
Q-score: 0.35
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ Pubmed: 32783883 DOI: doi:10.1016/j.chom.2020.07.008 ]
- Mayaro virus (Virus from Mayaro virus)
- Fab chk-265 (Complex from Homo sapiens)
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Mayaro virus-fab chk-265 complex (Complex)
- E1 glycoprotein (41 kDa, Protein from Mayaro virus (strain Brazil))
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Mayaro virus (strain Brazil))
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6wds
Q-score: 0.631
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Ev68-159 heavy chain (13 kDa, Protein from Homo sapiens)
- Human antibody ev68-159 (Complex from Homo sapiens)
- Enterovirus d68 in complex with human monoclonal antibody ev68-159 (Complex)
- Ev68-159 light chain (11 kDa, Protein from Homo sapiens)
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Enterovirus d68 (Virus from Enterovirus D68)
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wdt
Q-score: 0.589
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Human monoclonal antibody ev68-228 (Complex from Homo sapiens)
- Ev68-228 heavy chain (14 kDa, Protein from Homo sapiens)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Enterovirus d68 in complex with human monoclonal antibody ev68-228 (Complex)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Ev68-228 light chain (11 kDa, Protein from Homo sapiens)
- Enterovirus d68 (Virus from Enterovirus D68)
Rhinovirus C15 complexed with domain I of receptor CDHR3
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6ppo
Q-score: 0.581
Sun Y, Watters K, Hill MG, Fang Q, Liu Y, Kuhn RJ, Klose T, Rossmann MG, Palmenberg AC
PNAS (2020) 117 pp. 6784-6791 [ DOI: doi:10.1073/pnas.1921640117 Pubmed: 32152109 ]
- Capsid protein vp4 (7 kDa, Protein from Rhinovirus C)
- Capsid protein vp1 (31 kDa, Protein from Rhinovirus C)
- Rhinovirus c (Virus from Rhinovirus C)
- Cadherin-related family member 3 (14 kDa, Protein from Homo sapiens)
- Complex of rhinovirus c15 with domain i from human cdhr3 (6 MDa, Complex)
- Calcium ion (40 Da, Ligand)
- Capsid protein vp2 (29 kDa, Protein from Rhinovirus C)
- Domain i from human cdhr3 (Complex from Homo sapiens)
- Capsid protein vp3 (25 kDa, Protein from Rhinovirus C)
Rhinovirus C15 complexed with domains I and II of receptor CDHR3
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6psf
Q-score: 0.554
Sun Y, Watters K, Hill MG, Fang Q, Liu Y, Kuhn RJ, Klose T, Rossmann MG, Palmenberg AC
PNAS (2020) 117 pp. 6784-6791 [ Pubmed: 32152109 DOI: doi:10.1073/pnas.1921640117 ]
- Capsid protein vp3 (25 kDa, Protein from Rhinovirus C)
- Capsid protein vp2 (29 kDa, Protein from Rhinovirus C)
- Rhinovirus c (Virus from Rhinovirus C)
- Capsid protein vp4 (7 kDa, Protein from Rhinovirus C)
- Domain i and domain ii (ec1-2) from human cdhr3 (Complex from Homo sapiens)
- Complex of rhinovirus c15 with domain i and domain ii (ec1-2) from human cdhr3 (6 MDa, Complex)
- Cadherin-related family member 3 (26 kDa, Protein from Homo sapiens)
- Capsid protein vp1 (31 kDa, Protein from Rhinovirus C)
Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 Fab
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6nqd
Q-score: 0.423
Ananthaswamy N, Fang Q, AlSalmi W, Jain S, Chen Z, Klose T, Sun Y, Liu Y, Mahalingam M, Chand S, Tovanabutra S, Robb ML, Rossmann MG, Rao VB
Nat Commun (2019) 10 pp. 873-873 [ Pubmed: 30787293 DOI: doi:10.1038/s41467-019-08825-7 ]
- 8anc195 g52k5 light chain (23 kDa, Protein from Homo sapiens)
- T/f100 env trimer (Complex from Human immunodeficiency virus 1)
- T/f100 env gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- 8anc195 g52k5 heavy chain, ig gamma-1 chain (26 kDa, Protein from Homo sapiens)
- T/f100 env trimer-8anc195 fab complex (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 8anc195 fab (Complex from Homo sapiens)
- T/f100 env gp41 (20 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ Pubmed: 30642974 DOI: doi:10.1073/pnas.1815432116 ]
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))