Resolution: 6.33 Å
EM Method: Single-particle
Fitted PDBs: 6vyv
Q-score: 0.339
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ DOI: doi:10.1016/j.chom.2020.07.008 Pubmed: 32783883 ]
- E1 glycoprotein (42 kDa, Protein from Ross river virus (strain T48))
- Ross river virus (strain t48) (Virus from Ross river virus (strain T48))
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
- E2 glycoprotein (38 kDa, Protein from Ross river virus (strain T48))
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w09
Q-score: 0.34
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ DOI: doi:10.1016/j.chom.2020.07.008 Pubmed: 32783883 ]
- E2 glycoprotein (38 kDa, Protein from Chikungunya virus)
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
- Chikungunya virus-fab complex (Complex)
- E3 (6 kDa, Protein from Chikungunya virus)
- E1 glycoprotein (42 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Virus from Chikungunya virus)
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6w1c
Q-score: 0.35
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe Jr JE
Cell Host Microbe (2020) 28 pp. 699-711.e7 [ DOI: doi:10.1016/j.chom.2020.07.008 Pubmed: 32783883 ]
- Mayaro virus-fab chk-265 complex (Complex)
- Mayaro virus (Virus from Mayaro virus)
- E2 glycoprotein (38 kDa, Protein from Mayaro virus (strain Brazil))
- Fab chk-265 light chain (22 kDa, Protein from Homo sapiens)
- Fab chk-265 (Complex from Homo sapiens)
- E1 glycoprotein (41 kDa, Protein from Mayaro virus (strain Brazil))
- Fab chk-265 heavy chain (23 kDa, Protein from Homo sapiens)
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6wds
Q-score: 0.631
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Ev68-159 heavy chain (13 kDa, Protein from Homo sapiens)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Enterovirus d68 in complex with human monoclonal antibody ev68-159 (Complex)
- Enterovirus d68 (Virus from Enterovirus D68)
- Human antibody ev68-159 (Complex from Homo sapiens)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Ev68-159 light chain (11 kDa, Protein from Homo sapiens)
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wdt
Q-score: 0.589
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Enterovirus d68 in complex with human monoclonal antibody ev68-228 (Complex)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Ev68-228 heavy chain (14 kDa, Protein from Homo sapiens)
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Enterovirus d68 (Virus from Enterovirus D68)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Human monoclonal antibody ev68-228 (Complex from Homo sapiens)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Ev68-228 light chain (11 kDa, Protein from Homo sapiens)
Rhinovirus C15 complexed with domain I of receptor CDHR3
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6ppo
Q-score: 0.581
Sun Y, Watters K, Hill MG, Fang Q, Liu Y, Kuhn RJ, Klose T, Rossmann MG, Palmenberg AC
PNAS (2020) 117 pp. 6784-6791 [ DOI: doi:10.1073/pnas.1921640117 Pubmed: 32152109 ]
- Domain i from human cdhr3 (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Complex of rhinovirus c15 with domain i from human cdhr3 (6 MDa, Complex)
- Capsid protein vp3 (25 kDa, Protein from Rhinovirus C)
- Capsid protein vp2 (29 kDa, Protein from Rhinovirus C)
- Capsid protein vp4 (7 kDa, Protein from Rhinovirus C)
- Capsid protein vp1 (31 kDa, Protein from Rhinovirus C)
- Cadherin-related family member 3 (14 kDa, Protein from Homo sapiens)
- Rhinovirus c (Virus from Rhinovirus C)
Rhinovirus C15 complexed with domains I and II of receptor CDHR3
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6psf
Q-score: 0.554
Sun Y, Watters K, Hill MG, Fang Q, Liu Y, Kuhn RJ, Klose T, Rossmann MG, Palmenberg AC
PNAS (2020) 117 pp. 6784-6791 [ DOI: doi:10.1073/pnas.1921640117 Pubmed: 32152109 ]
- Cadherin-related family member 3 (26 kDa, Protein from Homo sapiens)
- Complex of rhinovirus c15 with domain i and domain ii (ec1-2) from human cdhr3 (6 MDa, Complex)
- Domain i and domain ii (ec1-2) from human cdhr3 (Complex from Homo sapiens)
- Capsid protein vp3 (25 kDa, Protein from Rhinovirus C)
- Capsid protein vp2 (29 kDa, Protein from Rhinovirus C)
- Capsid protein vp4 (7 kDa, Protein from Rhinovirus C)
- Capsid protein vp1 (31 kDa, Protein from Rhinovirus C)
- Rhinovirus c (Virus from Rhinovirus C)
Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 Fab
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6nqd
Q-score: 0.423
Ananthaswamy N, Fang Q, AlSalmi W, Jain S, Chen Z, Klose T, Sun Y, Liu Y, Mahalingam M, Chand S, Tovanabutra S, Robb ML, Rossmann MG, Rao VB
Nat Commun (2019) 10 pp. 873-873 [ Pubmed: 30787293 DOI: doi:10.1038/s41467-019-08825-7 ]
- T/f100 env trimer (Complex from Human immunodeficiency virus 1)
- T/f100 env trimer-8anc195 fab complex (Complex)
- T/f100 env gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- 8anc195 g52k5 heavy chain, ig gamma-1 chain (26 kDa, Protein from Homo sapiens)
- 8anc195 g52k5 light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- T/f100 env gp41 (20 kDa, Protein from Human immunodeficiency virus 1)
- 8anc195 fab (Complex from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ Pubmed: 30642974 DOI: doi:10.1073/pnas.1815432116 ]
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody
Resolution: 7.7 Å
EM Method: Single-particle
Fitted PDBs: 6mui
Q-score: 0.075
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- E2 (53 kDa, Protein from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-42 antibody heavy chain (23 kDa, Protein from Mus musculus)
- Eeev-42 antibody light chain (23 kDa, Protein from Mus musculus)
- Eeev-42 fab (Complex from Mus musculus)
- Eastern equine encephalitis virus / eeev-42 fab complex (Complex)