Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8vcv
Q-score: 0.579
Brouwer PJM, Perrett HR, Beaumont T, Nijhuis H, Kruijer S, Burger JA, Bontjer I, Lee WH, Ferguson JA, Schauflinger M, Muller-Krauter H, Sanders RW, Strecker T, van Gils MJ, Ward AB
Cell Rep (2024) 43 pp. 114708-114708 [ DOI: doi:10.1016/j.celrep.2024.114708 Pubmed: 39243373 ]
- Rabbit polyclonal fv heavy chain (10 kDa, Protein from Oryctolagus cuniculus)
- Lineage iv lassa virus glycoprotein (josiah) in complex with rabbit polyclonal antibody (gpc-c epitope) (Complex from Oryctolagus cuniculus)
- Glycoprotein g2 (44 kDa, Protein from Lassa virus Josiah)
- Glycoprotein g1 (29 kDa, Protein from Lassa virus Josiah)
- Rabbit polyclonal fv light chain (9 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8ve8
Q-score: 0.599
Brouwer PJM, Perrett HR, Beaumont T, Nijhuis H, Kruijer S, Burger JA, Bontjer I, Lee WH, Ferguson JA, Schauflinger M, Muller-Krauter H, Sanders RW, Strecker T, van Gils MJ, Ward AB
Cell Rep (2024) 43 pp. 114708-114708 [ DOI: doi:10.1016/j.celrep.2024.114708 Pubmed: 39243373 ]
- Rabbit polyclonal fv heavy chain (10 kDa, Protein from Oryctolagus cuniculus)
- Glycoprotein g2 (44 kDa, Protein from Lassa virus Josiah)
- Glycoprotein g1 (29 kDa, Protein from Lassa virus Josiah)
- Lineage iv lassa virus glycoprotein (josiah) in complex with rabbit polyclonal antibody (gp1-a epitope) (Complex from Oryctolagus cuniculus)
- Rabbit polyclonal fv light chain (9 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Native Lassa glycoprotein in complex with neutralizing antibodies 12.1F and 37.2D
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 7uov
Q-score: 0.541
Li H, Buck T, Zandonatti M, Yin J, Moon-Walker A, Fang J, Koval A, Heinrich ML, Rowland MM, Diaz Avalos R, Schendel SL, Parekh D, Zyla D, Enriquez A, Harkins S, Sullivan B, Smith V, Chukwudozie O, Watanabe R, Robinson JE, Garry RF, Branco LM, Hastie KM, Saphire EO
Sci Transl Med (2022) 14 pp. eabq0991-eabq0991 [ DOI: doi:10.1126/scitranslmed.abq0991 Pubmed: 36288283 ]
- 37.2d light chain (variable domain) (11 kDa, Protein from Homo sapiens)
- Glycoprotein g2 (26 kDa, Protein from Lassa virus)
- Native lassa glycoprotein in complex with 12.1f-scfv and 37.2d-scfv (Complex)
- 37.2d heavy chain (variable domain) (13 kDa, Protein from Homo sapiens)
- 12.1f heavy chain (variable domain) (12 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 12.1f light chain (variable domain) (11 kDa, Protein from Homo sapiens)
- Glycoprotein g1 (29 kDa, Protein from Lassa virus)