Resolution: 2.15 Å
EM Method: Single-particle
Fitted PDBs: 9fjc
Q-score: 0.687
Soppela S, Plavec Z, Grohn S, Jartti M, Oikarinen S, Laajala M, Marjomaki V, Butcher SJ, Hankaniemi MM
Res Sq (2024) [ Pubmed: 38978565 DOI: doi:10.21203/rs.3.rs-4545395/v1 ]
- Capsid protein vp4 (1 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp3 (26 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp1 (25 kDa, Protein from Coxsackievirus B1)
- Palmitic acid (256 Da, Ligand)
Resolution: 2.15 Å
EM Method: Single-particle
Fitted PDBs: 9fjd
Q-score: 0.636
Soppela S, Plavec Z, Grohn S, Jartti M, Oikarinen S, Laajala M, Marjomaki V, Butcher SJ, Hankaniemi MM
Res Sq (2024) [ Pubmed: 38978565 DOI: doi:10.21203/rs.3.rs-4545395/v1 ]
- Capsid protein vp3 (25 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp1 (25 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
Compact formalin inactivated CVB1
Soppela S, Plavec Z, Grohn S, Jartti M, Oikarinen S, Laajala M, Marjomaki V, Butcher SJ, Hankaniemi MM
Res Sq (2024) [ Pubmed: 38978565 DOI: doi:10.21203/rs.3.rs-4545395/v1 ]
Expanded formalin inactivated CVB1
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9fje
Q-score: -0.025
Soppela S, Plavec Z, Grohn S, Jartti M, Oikarinen S, Laajala M, Marjomaki V, Butcher SJ, Hankaniemi MM
Res Sq (2024) [ Pubmed: 38978565 DOI: doi:10.21203/rs.3.rs-4545395/v1 ]
- Capsid protein vp3 (25 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp1 (25 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp2 (27 kDa, Protein from Coxsackievirus B1)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 8A10 (CVB1-A:8A10)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 7x35
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
- Coxsackievirus b1 (Virus from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 7x3y
Q-score: 0.557
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279-1294.e6 [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 9a3 heavy chain (13 kDa, Protein from Mus musculus)
- 9a3 light chain (11 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 empty particle in complex with nab 9a3 (cvb1-e:9a3) (Complex from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 2E6 (CVB1-E:2E6)
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7x2g
Q-score: 0.515
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 empty particle in complex with nab 2e6 (cvb1-e:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 pre-A particle in complex with nAb 2E6 (CVB1-pre-A:2E6)
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 7x2i
Q-score: 0.537
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Cryo-em structure of coxsackievirus b1 pre-a particle in complex with nab 2e6 (cvb1-pre-a:2e6) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 2E6 (CVB1-M:2E6)
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 7x2o
Q-score: 0.591
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 2e6 heavy chain (13 kDa, Protein from Mus musculus)
- 2e6 light chain (11 kDa, Protein from Mus musculus)
- Cryo-em structure of coxsackievirus b1 mature virion in complex with nab 2e6 (cvb1-m:2e6) (Complex from Coxsackievirus B1)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Palmitic acid (256 Da, Ligand)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (CVB1-M:8A10)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7x2t
Q-score: 0.531
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N
Cell Host Microbe (2022) 30 pp. 1279- [ Pubmed: 36002016 DOI: doi:10.1016/j.chom.2022.08.001 ]
- Virion protein 1 (31 kDa, Protein from Coxsackievirus B1)
- 8a10 light chain (11 kDa, Protein from Mus musculus)
- 8a10 heavy chain (13 kDa, Protein from Mus musculus)
- Vp3 (26 kDa, Protein from Coxsackievirus B1)
- Capsid protein vp4 (7 kDa, Protein from Coxsackievirus B1)
- Palmitic acid (256 Da, Ligand)
- Vp2 (29 kDa, Protein from Coxsackievirus B1)
- Cryo-em structure of coxsackievirus b1 mature virion in complex with nab 8a10 (cvb1-m:8a10) (Complex from Coxsackievirus B1)