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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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natural_source_ncbi_code:"285006" AND xref_links:"chebi"

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EMD-9218

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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

Release date: Nov. 21, 2018
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6mse
Q-score: 0.355

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y

Nature (2019) 565 pp. 49-55 [ Pubmed: 30479383 DOI: doi:10.1038/s41586-018-0736-4 ]

Sample:

26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
26s proteasome non-atpase regulatory subunit 2 (98 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
Substrate (2 kDa, Protein from Saccharomyces cerevisiae RM11-1a)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
Proteasome (Complex from Homo sapiens)
Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
Ubiquitin (8 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)

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EMD-9219

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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

Release date: Nov. 21, 2018
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6msg
Q-score: 0.34

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y

Nature (2019) 565 pp. 49-55 [ Pubmed: 30479383 DOI: doi:10.1038/s41586-018-0736-4 ]

Sample:

26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
26s proteasome non-atpase regulatory subunit 2 (98 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
Proteasome (Complex from Homo sapiens)
Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
Ubiquitin (8 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
Substrate (2 kDa, Protein from Saccharomyces cerevisiae RM11-1a)
26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)

[Show more]

EMD-9220

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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

Release date: Nov. 21, 2018
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6msh
Q-score: 0.322

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y

Nature (2019) 565 pp. 49-55 [ Pubmed: 30479383 DOI: doi:10.1038/s41586-018-0736-4 ]

Sample:

26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
Substrate (1 kDa, Protein from Saccharomyces cerevisiae RM11-1a)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 2 (98 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 4 (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
Proteasome (Complex from Homo sapiens)
Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)

[Show more]

EMD-9221

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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

Release date: Nov. 21, 2018
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6msj
Q-score: 0.373

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y

Nature (2019) 565 pp. 49-55 [ Pubmed: 30479383 DOI: doi:10.1038/s41586-018-0736-4 ]

Sample:

26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
26s proteasome non-atpase regulatory subunit 2 (98 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-6 (26 kDa, Protein from Homo sapiens)
Rpt2, np_002793.2 (26sha chain b) (49 kDa, Protein from Homo sapiens)
Substrate (3 kDa, Protein from Saccharomyces cerevisiae RM11-1a)
26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
Proteasome (Complex from Homo sapiens)
Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)

[Show more]

EMD-9222

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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

Release date: Nov. 21, 2018
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6msk
Q-score: 0.355

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y

Nature (2019) 565 pp. 49-55 [ Pubmed: 30479383 DOI: doi:10.1038/s41586-018-0736-4 ]

Sample:

26s proteasome regulatory subunit 10b (45 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-7 (27 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
26s proteasome regulatory subunit 7 (48 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-4 (29 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-7 (29 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-2 (25 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
26s proteasome non-atpase regulatory subunit 2 (98 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 12 (52 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 11 (47 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 7 (37 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 8 (39 kDa, Protein from Homo sapiens)
Rpt2, np_002793.2 (26sha chain b) (49 kDa, Protein from Homo sapiens)
Substrate (3 kDa, Protein from Saccharomyces cerevisiae RM11-1a)
26s proteasome regulatory subunit 6a (49 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 13 (42 kDa, Protein from Homo sapiens)
26s proteasome complex subunit sem1 (8 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 3 (60 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-4 (29 kDa, Protein from Homo sapiens)
Proteasome (Complex from Homo sapiens)
Proteasome subunit alpha type-6 (27 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-2 (22 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Proteasome subunit beta type-5 (28 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-3 (28 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-3 (22 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-5 (26 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-6 (25 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 14 (34 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 6 (45 kDa, Protein from Homo sapiens)
Adenosine-5'-triphosphate (507 Da, Ligand)
26s proteasome regulatory subunit 8 (44 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 4 (40 kDa, Protein from Homo sapiens)
26s proteasome non-atpase regulatory subunit 1 (105 kDa, Protein from Homo sapiens)
Proteasome subunit alpha type-1 (30 kDa, Protein from Homo sapiens)
Proteasome subunit beta type-1 (26 kDa, Protein from Homo sapiens)
26s proteasome regulatory subunit 6b (47 kDa, Protein from Homo sapiens)

[Show more]

EMD-7023

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Mitochondrial ATPase Protease YME1

Release date: Nov. 15, 2017
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6az0

Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC

Science (2017) 358 [ Pubmed: 29097521 DOI: doi:10.1126/science.aao0464 ]

Sample:

Magnesium ion (24 Da, Ligand)
Adenosine-5'-triphosphate (507 Da, Ligand)
Adenosine-5'-diphosphate (427 Da, Ligand)
Zinc ion (65 Da, Ligand)
Poly(unk) (869 Da, Protein from Escherichia coli)
Yme1 atpase protease walker b mutant bound to substrate (295 kDa, Complex from Saccharomyces cerevisiae)
Mitochondrial inner membrane i-aaa protease supercomplex subunit yme1 (48 kDa, Protein from Saccharomyces cerevisiae (strain RM11-1a))

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Showing 1 - 6 of 6. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [6]

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Select the script type:

Shell (Unix-based) Batch (Windows-based)

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