Structure of E6AP-E6 complex in Att2 state
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8jro
Q-score: 0.492
Wang Z, Fan F, Li Z, Ye F, Wang Q, Gao R, Qiu J, Lv Y, Lin M, Xu W, Luo C, Yu X
Nat Commun (2024) 15 pp. 3531-3531 [ DOI: doi:10.1038/s41467-024-47586-w Pubmed: 38670961 ]
- Ubiquitin-protein ligase e3a (100 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- E6ap-e6 complex (Complex from Homo sapiens)
- Protein e6 (19 kDa, Protein from Human papillomavirus 16)
Structure of E6AP-E6 complex in Att3 state
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 8jrp
Q-score: 0.34
Wang Z, Fan F, Li Z, Ye F, Wang Q, Gao R, Qiu J, Lv Y, Lin M, Xu W, Luo C, Yu X
Nat Commun (2024) 15 pp. 3531-3531 [ DOI: doi:10.1038/s41467-024-47586-w Pubmed: 38670961 ]
- Ubiquitin-protein ligase e3a (100 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- E6ap-e6 complex (Complex from Homo sapiens)
- Protein e6 (17 kDa, Protein from Human papillomavirus 16)
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8gcr
Q-score: 0.468
Wang JCK, Baddock HT, Mafi A, Foe IT, Bratkowski M, Lin TY, Jensvold ZD, Preciado Lopez M, Stokoe D, Eaton D, Hao Q, Nile AH
Nat Commun (2024) 15 pp. 1842-1842 [ DOI: doi:10.1038/s41467-024-45920-w Pubmed: 38418456 ]
- Zinc ion (65 Da, Ligand)
- E6ap (Complex from Homo sapiens)
- Maltose/maltodextrin-binding periplasmic protein,protein e6 (61 kDa, Protein from Human papillomavirus type 16)
- Ternary complex of hpv16 e6, e6ap, and p53 (Complex)
- Ubiquitin-protein ligase e3a (104 kDa, Protein from Homo sapiens)
- Cellular tumor antigen p53 (24 kDa, Protein from Homo sapiens)
- Hpv16 e6 - mbp fusion (Complex from Escherichia coli)
- P53 (Complex from Homo sapiens)
Monomeric E6AP-E6-p53 ternary complex
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8r1f
Q-score: 0.316
Sandate CR, Chakraborty D, Kater L, Kempf G, Thoma NH
bioRxiv (2023) [ DOI: doi:10.1101/2023.11.01.565136 ]
- Zinc ion (65 Da, Ligand)
- Cellular tumor antigen p53 (46 kDa, Protein from Homo sapiens)
- Ubiquitin-like protein smt3,protein e6 (31 kDa, Protein from Human papillomavirus type 16)
- Ubiquitin-protein ligase e3a (103 kDa, Protein from Homo sapiens)
- Monomeric e6ap-e6-p53 ternary complex (176 kDa, Complex from Homo sapiens)
Dimeric ternary structure of E6AP-E6-p53
Resolution: 3.99 Å
EM Method: Single-particle
Fitted PDBs: 8r1g
Q-score: 0.175
Sandate CR, Chakraborty D, Kater L, Kempf G, Thoma NH
bioRxiv (2023) [ DOI: doi:10.1101/2023.11.01.565136 ]
- Zinc ion (65 Da, Ligand)
- Cellular tumor antigen p53 (46 kDa, Protein from Homo sapiens)
- Ubiquitin-like protein smt3,protein e6 (31 kDa, Protein from Human papillomavirus type 16)
- Ubiquitin-protein ligase e3a (103 kDa, Protein from Homo sapiens)
- Dimeric e6ap-e6-p53 ternary complex (352 kDa, Complex from Homo sapiens)