Kril V, Hons M, Amadori C, Zimberger C, Couture L, Bouery Y, Burlaud-Gaillard J, Karpov A, Ptchelkine D, Thienel AL, Kummerer BM, Desfosses A, Jones R, Roingeard P, Meertens L, Amara A, Reguera J
Nat Commun (2024) 15 pp. 8106-8106 [ Pubmed: 39285216 DOI: doi:10.1038/s41467-024-51952-z ]
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8apx
Q-score: 0.391
Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J
PNAS (2023) 120 pp. e2213934120-e2213934120 [ Pubmed: 36913573 DOI: doi:10.1073/pnas.2213934120 ]
- Chikv nsp1 capping pores covalently linked to m7gmp cap via h37 (720 kDa, Complex from Chikungunya virus strain S27-African prototype)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Polyprotein p1234 (53 kDa, Protein from Chikungunya virus strain S27-African prototype)
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with m7GTP and SAH ligands
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8aow
Q-score: 0.584
Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J
PNAS (2023) 120 pp. e2213934120-e2213934120 [ Pubmed: 36913573 DOI: doi:10.1073/pnas.2213934120 ]
- Zinc ion (65 Da, Ligand)
- Chikv nsp1 capping pores in complex with m7gtp and sah ligand with magnesium cofactor. (720 kDa, Complex from Chikungunya virus strain S27-African prototype)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- 7-methyl-guanosine-5'-triphosphate (538 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mrna-capping enzyme nsp1 (60 kDa, Protein from Chikungunya virus strain S27-African prototype)
- Water (18 Da, Ligand)
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with SAM
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8aox
Q-score: 0.574
Jones R, Hons M, Rabah N, Zamarreno N, Arranz R, Reguera J
PNAS (2023) 120 pp. e2213934120-e2213934120 [ Pubmed: 36913573 DOI: doi:10.1073/pnas.2213934120 ]
- Zinc ion (65 Da, Ligand)
- Mrna-capping enzyme nsp1 (59 kDa, Protein from Chikungunya virus strain S27-African prototype)
- S-adenosylmethionine (398 Da, Ligand)
- Chikv nsp1 capping pores in complex with s-adenosyl methionine (sam) ligand. (1 MDa, Complex from Chikungunya virus strain S27-African prototype)
- Water (18 Da, Ligand)
Cryo-EM map of Chikungunya virus strain s27
Mangala Prasad V, Blijleven JS, Smit JM, Lee KK
Nat Commun (2022) 13 pp. 4772-4772 [ Pubmed: 35970990 DOI: doi:10.1038/s41467-022-32431-9 ]
CryoEM structure of the Chikungunya virus nsP1 complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6z0u
Q-score: 0.595
Jones R, Bragagnolo G, Arranz R, Reguera J
Nature (2021) 589 pp. 615-619 [ Pubmed: 33328629 DOI: doi:10.1038/s41586-020-3036-8 ]
- Polyprotein p1234 (53 kDa, Protein from Chikungunya virus strain S27-African prototype)
- Zinc ion (65 Da, Ligand)
- Water (18 Da, Ligand)
- Chikungunya nsp1 capping pore complex (1 MDa, Complex from Chikungunya virus strain S27-African prototype)
CryoEM structure of the Chikungunya virus nsP1 complex
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 6z0v
Q-score: 0.637
Jones R, Bragagnolo G, Arranz R, Reguera J
Nature (2021) 589 pp. 615-619 [ Pubmed: 33328629 DOI: doi:10.1038/s41586-020-3036-8 ]
- Polyprotein p1234 (53 kDa, Protein from Chikungunya virus strain S27-African prototype)
- Zinc ion (65 Da, Ligand)
- Water (18 Da, Ligand)
- Chikungunya nsp1 capping pore complex (720 kDa, Complex from Chikungunya virus strain S27-African prototype)